The Inflammation Research Center includes three scientific axes:
Axis 1 – Pathophysiology of inflammatory & fibrotic diseases
Identify the common characteristics of inflammatory mechanisms in immune cells, endothelial cells and fibroblasts (lungs/kidneys/digestive tract)
Axis 2 – Oncogenic inflammation & tumor development
Decipher the sequence of pro-oncogenic events in the context of inflammation characterize tumor heterogeneity via the tumor microenvironment
Axis 3 – Signaling and dynamics of immune cells
Describe the molecular mechanisms of the inflammatory response, in particular oxidative stress and intracellular trafficking