EXTRACELLULAR VESICLES

Extracellular vesicles are involved in the development of different diseases. Due to their implication they can be used as biomarkers.

The platform offers users, from human or murine samples, or cultured cells, to train in the techniques of generation, isolation and characterization of vesicles.

 

EQUIPMENT

– Exoid

– Colonne SEC

– Cytoflex

– Ultracentrifugeuse Beckman

 

 

More information on extracellular vesicles

  • Théry C. et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018). J Extracell vesicles. 2018;7:1535750
  • Coumans F. et al. Methodological guidelines to study extracellular vesicles. Circ Res . 2017; 120:1632-4
  • Ridger VC et al. Microvesicles in vascular homeostasis and diseases. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology. Thromb Haemost.2017;117:1296-1316

Some of our recent studies on extracellular vesicles

  • Elkrief L. et al. Hepatocyte-derived biomarkers predict liver-related events at 2 years in Child-Pugh class A alcohol-related cirrhosis. Journal of Hepatology. 2023
  • Payancé A. et al. Hepatocyte microvesicle levels improve prediction of mortality in patients with cirrhosis. Hepatology. 2018 Oct;68:1508-1518
  • Bissonnette J et al. A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis. Hepatology. 2017;66:555-563
  • Lemoinne S et al. The emerging roles of microvesicles in liver diseases. Nat Rev Gastroenterol Hepatol. 2014;11:350-61

 

RESERVE

Responsable Scientifique

Responsable Technique