Childcare facility
Department/Unit/Institute:
Laboratory of Immunopathology, Nephrology and Cell Signaling (LINCS) Eq. Charles, INSERM – UMR 1149 – Centre de recherche sur l’inflammation (CRI), Université Paris Cité, Faculté de médecine site Bichat, 16 rue Henri Huchard, 75018 Paris.
About the Organisation
The Centre for Research on Inflammation (CRI) is a joint Inserm/Université Paris Cité/CNRS research unit headed by Prof. Valérie PARADIS. It comprises fourteen research teams organised across three cross-cutting scientific areas (Pathophysiology of inflammatory and fibrotic diseases; Oncogenic inflammation and tumour development; Immunology, Cell Signalling and Dynamics) and two junior research groups. The research centre brings together around 330 people: researchers (Inserm, CNRS, international researchers), academic researchers and hospital staff (Université Paris), engineers, technicians, students (PhD, Master’s, engineering school students, etc.), several technical facilities and platforms, and support services. https://cri1149.fr/
The Laboratory of Immunopathology, Nephrology and Cell Signalling (LINCS) at the Centre for Research on Inflammation (INSERM U1149, CNRS EMR 8252, Université Paris Cité), led by Nicolas Charles, comprises 10 researchers and lecturer-researchers, 3 technicians and engineers, 6 PhD students, 3 Master’s 2 students and 2 postdoctoral researchers. As part of a project funded by the ANR, the team is seeking a candidate for the post of engineering assistant. The team is particularly active in translational research into autoimmune diseases, with or without renal involvement (systemic lupus erythematosus, chronic kidney diseases, etc.), working in close collaboration with the nephrology and internal medicine departments at Bichat Hospital. In this context, we are looking for a candidate who is motivated by both the analysis of human samples (blood) and animal models (mice), and who wishes to work in an exceptional scientific and collegial environment 😊.
https://cri1149.fr/equipes/equipe-charles/
Director: Valérie PARADIS
Adresse : Faculté de Médecine Xavier Bichat, 16 rue Henri Huchard – Paris 18 ème
Regional Delegation: Paris-IDF Centre-North
Job description
Main mission
The assistant engineer will work closely with other members of the research team to carry out projects in the field of immunopathology.
Main activities:
- To manage the supply and inventory of a biobank (serum/plasma/DNA/PBMC).
- Manage the mouse strains in collaboration with other team members (genotyping, breeding strategies, animal monitoring).
- To contribute to in vivo experiments (in mice) aimed at understanding and controlling the development of autoimmune diseases.
- Keep the experimental protocols used by the team and the electronic laboratory logbook up to date.
- To analyse and present the results of tests at laboratory meetings and to ensure their quality.
- To contribute to the smooth running of the research team in coordination with the other members of the laboratory.
- Depending on the wishes and motivations of the person selected, the supervision of trainees and participation in a research project to be determined may be considered.
Job specifics and working environment:
- Second-year laboratory work on human samples.
- Research involving animals (mice).
- No other specific features.
Knowledge, Expertise, Skills:
- Experience in animal experimentation (mice) (at designer or experimenter level) and in mouse strain management.
- Proficiency in eukaryotic cell culture techniques and laboratory work (L2).
- Proficiency in basic molecular biology techniques (PCR, qPCR, RT)
- Proficiency and/or knowledge of immunological techniques (ELISA, flow cytometry, immunohistochemistry, immunofluorescence, etc.)
- Proficiency in IT tools (office software and scientific software) and good organisational skills.
- Work as part of a team and independently.
Desired experience(s):
Beginners welcome 😊
Qualification level and training
Minimum of a three-year degree (vocational bachelor’s degree, BUT, DUT or equivalent)
General Information
| Start date | As soon as possible (1 September 2026…) |
| Contract duration (fixed-term) | Renewable: ☒ YES ☐ NO |
| Working hours |
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| Activities that can be carried out remotely | ☐ YES * ☒ NO
* Following a period of induction and training. |
| Remuneration | Contract staff: In accordance with the current INSERM pay scale |
Application procedures
| Application deadline | 17 July 2026 |
| Contact | Nicolas CHARLES – nicolas.charles@inserm.fr |
| Application procedure | Please send your CV, covering letter and the contact details of two referees who can be contacted to nicolas.charles@inserm.fr |
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