- Department : Hepato-Gastroenterology Department
- Team : Paradis / Couvineau
- Fonction : Researcher(s)
- 01 57 27 74 87
- cecile.haumaitre@inserm.fr
- CV
Implication of epigenetics in pancreas development and disease.
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors.
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b.
Lack of TCF2/vHNF1 in mice leads to pancreas agenesis.