CRS - Chargé de Reherche Statutaire
Publications les plus marquantes :
- Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease.
J Pathol. 2021 May;254(1):31-45. PMID: 33527355
- Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis.
Cell Mol Gastroenterol Hepatol. 2019;8(3):487-511. PMID: 31229598.
- Implication of epigenetics in pancreas development and disease.
Best Pract Res Clin Endocrinol Metab. 2015 Dec;29(6):883-98. PMID: 26696517.
- Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors.
Development. 2015;142(5):871-82. PMID: 25715395. - Epigenetic regulation of pancreatic islets.
Curr Diab Rep. 2013;13(5):624-32.PMID: 23907485.
- Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b.
Nature. 2013;494(7435):111-5. PMID: 23389544.
- Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9.
Diabetes. 2011;60(11):2861-71. PMID: 21953612
- Directing cell differentiation with small-molecule histone deacetylase inhibitors: the example of promoting pancreatic endocrine cells.
Cell Cycle. 2009;8(4):536-44.PMID: 19197155
- Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors.
Mol Cell Biol. 2008;28(20):6373-83. PMID: 18710955
- Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutations.
Hum Mol Genet. 2006;15(15):2363-75. PMID: 16801329
- Lack of TCF2/vHNF1 in mice leads to pancreas agenesis.
Proc Natl Acad Sci U S A. 2005;102(5):1490-5. PMID: 15668393
N°ORCID : https://orcid.org/0000-0003-3526-7832
Publications marquantes
(3)
Acinar-to-Ductal Metaplasia (ADM): On the Road to Pancreatic Intraepithelial Neoplasia (PanIN) and Pancreatic Cancer
Int J Mol Sci.
09 Juin 2023
Auteurs :
Louis Marstrand-Daucé,
Diane Lorenzo,
Anaïs Chassac,
Pascal Nicole,
Anne Couvelard,
Cécile Haumaitre,
01 Mai 2021
Auteurs :
Evans Quilichini,
Mélanie Fabre,
Christoffer Nord,
Thassadite Dirami,
Axelle Le Marec,
Silvia Cereghini,
Raymond C Pasek,
Maureen Gannon,
Ulf Ahlgren,
Cécile Haumaitre,
Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis
Cell Mol Gastroenterol Hepatol.
20 Juin 2019
Auteurs :
Evans Quilichini,
Mélanie Fabre,
Thassadite Dirami,
Aline Stedman,
Matias De Vas,
Ozge Ozguc,
Raymond C Pasek,
Silvia Cereghini,
Lucie Morillon,
Carmen Guerra,
Anne Couvelard,
Maureen Gannon,
Cécile Haumaitre,