Publications

• Publication date : 23 April 2025 More

  Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation

  Nature Communications

  Authors : Al Sayegh Rola Wan Jinghong Caër Charles Azoulai Margot Maxime Gasperment Sukriti Baweja Marc-Anthony Chouillard Kandiah Janany Cadoux Mathilde Mabire Morgane Pignolet Camille Tristan Thibault-Sogorb Hammoutene Adel Paradis Valérie Saveanu Loredana Nicolle Rémy Gilgenkrantz Hélène Weiss Emmanuel Lotersztajn Sophie

• Publication date : 26 February 2024 More

  Predictive Role of Hepatic Venous Pressure Gradient in Bleeding Events Among Cirrhotic Patients Undergoing Orthotopic Liver Transplantation

  JHEP Rep.

  Authors : Mikhael Giabicani Pauline Joly Stéphanie Sigaut Clara Timsit Pauline Devauchelle Fédérica Dondero Durand François Pierre Antoine Froissant Myriam Lamamri Payancé Audrey Aymeric Restoux Olivier Roux Tristan Thibault-Sogorb Shantha Ram Valainathan Lesurtel Mickaël Rautou Pierre-Emmanuel Weiss Emmanuel

• Publication date : 31 July 2023 More

  Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)

  Gut.

  Authors : Weiss Emmanuel Carlos de la Peña-Ramirez Ferran Aguilar Juan-Jose Lozano Cristina Sánchez-Garrido Patricia Sierra Pedro Izquierdo-Bueno Martin Juan Manuel Diaz François Fenaille Florence A Castelli Gustot Thierry Wim Laleman Agustín Albillos Carlo Alessandria Marco Domenicali Paolo Caraceni Salvatore Piano Faouzi Saliba Stefan Zeuzem Alexander L Gerbes Julia A Wendon Christian Jansen Wenyi Gu Maria Papp Raj Mookerjee Carmine Gabriele Gambino Cesar Jiménez Ilaria Giovo Giacomo Zaccherini Manuela Merli Antonella Putignano Frank Erhard Uschner Thomas Berg Tony Bruns Christian Trautwein Alexander Zipprich Rafael Bañares José Presa Joan Genesca Victor Vargas Javier Fernández Mauro Bernardi Paolo Angeli Rajiv Jalan Joan Claria Christophe Junot Moreau Richard Jonel Trebicka Vicente Arroyo

• Publication date : 31 March 2023 More

  MAIT cell inhibition promotes liver fibrosis regression via macrophage phenotype reprogramming

  Nature Commun.

  Authors : Mabire Morgane Pushpa Hegde Hammoutene Adel Wan Jinghong Caër Charles Al Sayegh Rola Cadoux Mathilde Weiss Emmanuel Tristan Thibault-Sogorb Olivier Lantz Michèle Goodhardt Paradis Valérie Pierre de la Grange Gilgenkrantz Hélène Lotersztajn Sophie

• Publication date : 24 March 2023 More

  Evaluation of transcranial Doppler use in patients with acute liver failure listed for emergency liver transplantation

  Clin Transplant.

  Authors : Benjamin Picard Stéphanie Sigaut Olivier Roux Paër-Selim Abback Pierre-Marie Choinier Marina Hachouf Mikhael Giabicani Juliette Kavafyan Claire Francoz Federica Dondero Mickaël Lesurtel Durand François Cauchy François Paugam-Burtz Catherine Souhayl Dahmani Weiss Emmanuel

• Publication date : 04 February 2021 More

  Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF

  Front Immunol.

  Authors : Weiss Emmanuel Pierre de la Grange Mylène Defaye Juan José Lozano Ferrán Aguilar Pushpa Hegde Ariane Jolly Moga Lucile Sukriti Sukriti Banwari Agarwal Haqeeqat Gurm Tanguy Marion Poisson Johanne Joan Clària Paer-Selim Abback Perianin Axel Gautam Mehta Rajiv Jalan Francoz Claire Rautou Pierre-Emmanuel Lotersztajn Sophie Vicente Arroyo Durand François Moreau Richard

• Publication date : 14 April 2020 More

  LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling.

  Sci Transl Med

  Authors : Wan Jinghong Weiss Emmanuel Ben Mkaddem Sanae Mabire Morgane Pierre-Marie Choinier Olivia Picq Tristan Thibault-Sogorb Pushpa Hegde Dorsa Pishvaie Bens Marcelle Linda Broer Gilgenkrantz Hélène Moreau Richard Saveanu Loredana Patrice Codogno Monteiro Renato Lotersztajn Sophie

• Publication date : 05 September 2019 More

  Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.

  J Exp Med.

  Authors : Ohayon D De Chiara A Dang Pham My-Chan Thieblemont N Chatfield S Marzaioli V Burgener SS Mocek J Candalh C Pintard Coralie Tacnet-Delorme P Renault G Lagoutte I Favier M Walker Francine Hurtado-Nedelec Maria Margarita Desplancq D Weiss Emmanuel Benarafa C Housset D Marie Jean-Claude Frachet P El Benna Jamel Witko-Sarsat V

• Publication date : 08 October 2018 More

  Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

  Gut. 2018

  Authors : Habib Aida Chokr D Wan Jinghong Hegde P Mabire Morgane Siebert M Ribeiro-Parenti Lara Le Gall Maude Letteron Philippe Pilard N Mansouri Abdellah Brouillet A Tardelli M Weiss Emmanuel Le Faouder P Guillou H Cravatt BF Moreau Richard Trauner M Lotersztajn Sophie

• Publication date : 08 July 2018 More

  NADPH oxidase depletion in neutrophils from patients with cirrhosis and restoration via toll-like receptor 7/8 activation

  Gut. 2018;67(8):1505-1516

  Authors : Rolas L Boussif A Weiss Emmanuel Letteron Philippe Haddad O El Benna Jamel Rautou Pierre-Emmanuel Moreau Richard Perianin Axel

• Publication date : 31 May 2018 More

  Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver

  Nat Commun.

  Authors : Hegde P Weiss Emmanuel Paradis Valérie Wan Jinghong Mabire Morgane Sukriti S Rautou Pierre-Emmanuel Albuquerque Miguel Picq O Gupta AC Ferrere G Gilgenkrantz Hélène Kiaf B Toubal A Beaudoin L Letteron Philippe Moreau Richard Lehuen A Lotersztajn Sophie

• Publication date : 03 May 2016 More

  Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome

  J Hepatol. 2017 May;66(5):930-941

  Authors : Weiss Emmanuel Rautou Pierre-Emmanuel Fasseu M Giabicani M De Chambrun M Wan Jinghong Minsart C Gustot Thierry Couvineau Alain Maiwall Hurtado-Nedelec Maria Margarita Pilard N Lebrec D Valla Dominique Durand François De La Grange P Monteiro Renato Paugam-Burtz Catherine Lotersztajn Sophie Moreau Richard

• Publication date : 30 April 2016 More

  Impaired intracellular signaling, myeloperoxidase release and bactericidal activity of neutrophils from patients with alcoholic cirrhosis

  J Hepatol.

  Authors : Abdelali Boussif Loïc Rolas Weiss Emmanuel Hamama Bouriche Moreau Richard Perianin Axel