Hepatitis D Virus Infection

Authors

Mario Rizzetto,

Hepatitis D virus (HDV), also known as hepatitis delta virus, is a defective, hepatotropic pathogenic agent. The life cycle of HDV requires the hepatitis B surface antigen (HBsAg) provided by hepatitis B virus (HBV).¹ Like HBV, HDV is transmitted by the parenteral route through infectious body fluids; intravenous drug users are at highest risk for infection because of contaminated syringes.^2,3 Key features of the infection are its unique biologic characteristics and ominous medical effect. Clinical studies have shown that chronic hepatitis D is the most severe and progressive form of viral hepatitis in humans.² The infection is ubiquitous, yet 40 years after it was identified, the prevalence remains undetermined in many parts of the world. In three recent meta-analyses, the number of HDV-infected persons worldwide ranged from 12 million to 72 million, underscoring the heterogeneity of current epidemiologic data.³ Valid therapies to cure hepatitis D are an urgent need, and new therapeutic strategies are in development.

Other publications

Hepatitis-B virus: replication cycle, targets, and antiviral approaches

Curr Opin Virol.

Publication date :

08 Sep 2023

Authors :

Nour Nasser,

Pierre Tonnerre ,

Mansouri Abdellah,

Asselah Tarik,

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Hepatitis D double reflex testing of all hepatitis B carriers in low-HBV- and high-HBV/HDV-prevalence countries

J Hepatol.

Publication date :

31 Jul 2023

Authors :

Homie A Razavi,

Maria Buti,

Norah A Terrault,

Stefan Zeuzem,

Cihan Yurdaydin,

Junko Tanaka,

Alessio Aghemo,

Ulus S Akarca,

Nasser M Al Masri,

Abduljaleel M Alalwan,

Soo Aleman,

Abdullah S Alghamdi,

Saad Alghamdi,

Waleed K Al-Hamoudi,

Abdulrahman A Aljumah,

Ibrahim H Altraif,

Asselah Tarik,

Ziv Ben-Ari,

Thomas Berg,

Mia J Biondi,

Sarah Blach,

Wornei S M Braga,

Carlos E Brandão-Mello,

Maurizia R Brunetto,

Joaquin Cabezas,

Hugo Cheinquer,

Pei-Jer Chen,

Myeong-Eun Cheon,

Wan-Long Chuang,

Carla S Coffin,

Nicola Coppola,

Antonio Craxi,

Javier Crespo,

Victor De Ledinghen,

Ann-Sofi Duberg,

Ohad Etzion,

Maria Lucia G Ferraz,

Paulo R A Ferreira,

Xavier Forns,

Graham R Foster,

Giovanni B Gaeta,

Ivane Gamkrelidze,

Javier García-Samaniego,

Liliana S Gheorghe,

Pierre M Gholam,

Robert G Gish,

Jeffrey Glenn,

Julian Hercun,

Yao-Chun Hsu,

Ching-Chih Hu,

Jee-Fu Huang,

Naveed Janjua,

Jidong Jia,

Martin Kåberg,

Kelly D E Kaita,

Habiba Kamal,

Jia-Horng Kao,

Loreta A Kondili,

Martin Lagging,

Pablo Lázaro,

Jeffrey V Lazarus,

Mei-Hsuan Lee,

Young-Suk Lim,

Paul J Marotta,

Maria-Cristina Navas,

Marcelo C M Naveira,

Mauricio Orrego,

Carla Osiowy,

Calvin Q Pan,

Mário G Pessoa,

Giovanni Raimondo,

Alnoor Ramji,

Devin M Razavi-Shearer,

Kathryn Razavi-Shearer,

Cielo Y Ríos-Hincapié,

Manuel Rodríguez,

William M C Rosenberg,

Dominique M Roulot,

Stephen D Ryder,

Rifaat Safadi,

Faisal M Sanai,

Teresa A Santantonio,

Christoph Sarrazin,

Daniel Shouval,

Frank Tacke,

Tammo L Tergast ,

Juan Miguel Villalobos-Salcedo,

Alexis S Voeller,

Hwai-I Yang,

Ming-Lung Yu,

Eli Zuckerman,

Polaris Observatory,

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Molecular and Clinical Features of Hepatocellular Carcinoma in Patients with HBV-HDV Infection

J Hepatocell Carcinoma.

Publication date :

24 Apr 2023

Authors :

Federico Costante,

Leonardo Stella,

Francesco Santopaolo,

Antonio Gasbarrini,

Maurizio Pompili,

Asselah Tarik,

Francesca Romana Ponziani,

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Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology.

Publication date :

31 Mar 2023

Authors :

Loureiro Dimitri,

Tout Issam Alex,

Narguet Stéphanie,

Bed Cheikh Mohamed,

Morgane Roinard,

Ahmad Sleiman,

Boyer Nathalie,

Pons-Kerjean Nathalie,

Castelnau Corinne,

Nathalie Giuly,

Dorothy Tonui,

Vassili Soumelis,

El Benna Jamel,

Patrick Soussan,

Moreau Richard,

Paradis Valérie,

Mansouri Abdellah,

Asselah Tarik,

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