Authors
Abstract
Mucosal-associated invariant T (MAIT) cells are unique innate-like T cells that bridge innate and adaptive immunity. They are activated by conserved bacterial ligands derived from vitamin B biosynthesis and have important roles in defence against bacterial and viral infections. However, they can also have various deleterious and protective functions in autoimmune, inflammatory and metabolic diseases. MAIT cell involvement in a large spectrum of pathological conditions makes them attractive targets for potential therapeutic approaches.
Other publications
01 Jul 2021
Authors :
Moreau Richard,
[:fr]Bin Gao[:],
[:fr]Maria Papp[:],
[:fr]Rafael Bañares[:],
[:fr]Patrick S Kamath[:],
Targeting cell-intrinsic metabolism for antifibrotic therapy
[:en]J Hepatol.[:]
01 Jun 2021
Authors :
Gilgenkrantz Hélène,
Mallat Ariane,
Moreau Richard,
Lotersztajn Sophie,
Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF
[:fr]Front Immunol.[:]
05 Feb 2021
Authors :
Weiss Emmanuel,
Pierre de la Grange,
Mylène Defaye,
Juan José Lozano,
Ferrán Aguilar,
Pushpa Hegde,
Ariane Jolly,
Moga Lucile,
Sukriti Sukriti,
Banwari Agarwal,
Haqeeqat Gurm,
Tanguy Marion,
Poisson Johanne,
Joan Clària,
Paer-Selim Abback,
Perianin Axel,
Gautam Mehta,
Rajiv Jalan,
Francoz Claire,
Rautou Pierre-Emmanuel,
Lotersztajn Sophie,
Vicente Arroyo,
Durand François,
Moreau Richard,