Publications

• Publication date : 31 July 2023 More

  Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)

  Gut.

  Authors : Weiss Emmanuel Carlos de la Peña-Ramirez Ferran Aguilar Juan-Jose Lozano Cristina Sánchez-Garrido Patricia Sierra Pedro Izquierdo-Bueno Martin Juan Manuel Diaz François Fenaille Florence A Castelli Gustot Thierry Wim Laleman Agustín Albillos Carlo Alessandria Marco Domenicali Paolo Caraceni Salvatore Piano Faouzi Saliba Stefan Zeuzem Alexander L Gerbes Julia A Wendon Christian Jansen Wenyi Gu Maria Papp Raj Mookerjee Carmine Gabriele Gambino Cesar Jiménez Ilaria Giovo Giacomo Zaccherini Manuela Merli Antonella Putignano Frank Erhard Uschner Thomas Berg Tony Bruns Christian Trautwein Alexander Zipprich Rafael Bañares José Presa Joan Genesca Victor Vargas Javier Fernández Mauro Bernardi Paolo Angeli Rajiv Jalan Joan Claria Christophe Junot Moreau Richard Jonel Trebicka Vicente Arroyo

• Publication date : 29 May 2023 More

  Genetic Ancestry, Race, and Severity of Acutely Decompensated Cirrhosis in Latin America

  Gastroenterology.

  Authors : Alberto Queiroz Farias Anna Curto Vilalta Patrícia Momoyo Zitelli Gustavo Pereira Luciana L Goncalves Aldo Torre Juan Manuel Diaz Adrian C Gadano Angelo Z Mattos Liliana S C Mendes Mario R Alvares-da-Silva Paulo L Bittencourt Carlos Benitez Claudia Alves Couto Manuel Mendizabal Claudio L Toledo Daniel F Mazo Mauricio Castillo Barradas Eva M Uson Raposo P Martín Padilla-Machaca Adelina Zarela Lozano Miranda René Malé-Velázquez André Castro Lyra Milagros B Dávalos-Moscol Jose L Pérez Hernandez Rafael O Ximenes Giovanni Faria Silva Oscar A Beltrán-Galvis María S González Huezo Fernando Bessone Tarciso D S Rocha Eduardo Fassio Carlos Terra Juan I Marín Patricia Sierra Casas Carlos de la Peña-Ramirez Ferran Aguilar Parera Flavia Fernandes Maria da Penha Zago-Gomes Osvely Méndez-Guerrero Sebastián Marciano Angelo A Mattos Joao C Oliveira Gabriel T S Guerreiro Liana Codes Marco Arrese Mateus J Nardelli Marcelo O Silva Renato Palma-Fernandez Camila Alcantara Cristina Sánchez Garrido Jonel Trebicka Thierry Gustot Javier Fernández Joan Clària Rajiv Jalan Paolo Angeli Vicente Arroyo Moreau Richard Flair J Carrilho ACLARA Study Collaborators

• Publication date : 31 March 2023 More

  Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

  Hepatology.

  Authors : Loureiro Dimitri Tout Issam Alex Narguet Stéphanie Bed Cheikh Mohamed Morgane Roinard Ahmad Sleiman Boyer Nathalie Pons-Kerjean Nathalie Castelnau Corinne Nathalie Giuly Dorothy Tonui Vassili Soumelis El Benna Jamel Patrick Soussan Moreau Richard Paradis Valérie Mansouri Abdellah Asselah Tarik

• Publication date : 30 June 2021 More

  Acute-on-chronic liver failure: A distinct clinical syndrome

  J Hepatol .

  Authors : Moreau Richard Bin Gao Maria Papp Rafael Bañares Patrick S Kamath

• Publication date : 31 May 2021 More

  Targeting cell-intrinsic metabolism for antifibrotic therapy

  J Hepatol.

  Authors : Gilgenkrantz Hélène Mallat Ariane Moreau Richard Lotersztajn Sophie

• Publication date : 04 February 2021 More

  Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF

  Front Immunol.

  Authors : Weiss Emmanuel Pierre de la Grange Mylène Defaye Juan José Lozano Ferrán Aguilar Pushpa Hegde Ariane Jolly Moga Lucile Sukriti Sukriti Banwari Agarwal Haqeeqat Gurm Tanguy Marion Poisson Johanne Joan Clària Paer-Selim Abback Perianin Axel Gautam Mehta Rajiv Jalan Francoz Claire Rautou Pierre-Emmanuel Lotersztajn Sophie Vicente Arroyo Durand François Moreau Richard

• Publication date : 27 May 2020 More

  Acute-on-Chronic Liver Failure

  N Engl J Med.

  Authors : Vicente Arroyo Moreau Richard Rajiv Jalan

• Publication date : 14 April 2020 More

  LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling.

  Sci Transl Med

  Authors : Wan Jinghong Weiss Emmanuel Ben Mkaddem Sanae Mabire Morgane Pierre-Marie Choinier Olivia Picq Tristan Thibault-Sogorb Pushpa Hegde Dorsa Pishvaie Bens Marcelle Linda Broer Gilgenkrantz Hélène Moreau Richard Saveanu Loredana Patrice Codogno Monteiro Renato Lotersztajn Sophie

• Publication date : 07 May 2019 More

  Review of Defective NADPH Oxidase Activity and Myeloperoxidase Release in Neutrophils From Patients With Cirrhosis

  Front Immunol.

  Authors : Moreau Richard Perianin Axel Vicente Arroyo

• Publication date : 30 November 2018 More

  Effects of Long-term Norfloxacin Therapy in Patients With Advanced Cirrhosis

  Gastroenterology. 2018 Dec;155(6):1816-1827.May;66(5):930-941

  Authors : Moreau Richard Elkrief Laure Bureau C Perarnau JM Thévenot T Saliba F Louvet A Nahon P Lannes A Anty R Hillaire S Pasquet B Ozenne V Rudler M Ollivier-Hourmand I Robic MA Di Martino V Ripault MP Pauwels A Grangé JD Carbonell N Bronowicki JP Payancé A Rautou Pierre-Emmanuel Valla Dominique Gault N Lebrec D NORFLOCIR Trial Investigators

• Publication date : 08 October 2018 More

  Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

  Gut. 2018

  Authors : Habib Aida Chokr D Wan Jinghong Hegde P Mabire Morgane Siebert M Ribeiro-Parenti Lara Le Gall Maude Letteron Philippe Pilard N Mansouri Abdellah Brouillet A Tardelli M Weiss Emmanuel Le Faouder P Guillou H Cravatt BF Moreau Richard Trauner M Lotersztajn Sophie

• Publication date : 30 September 2018 More

  Hepatocyte microvesicle levels improve prediction of mortality in patients with cirrhosis.

  Hepatology

  Authors : Payancé A Silva-Junior G Bissonnette J Tanguy Marion Pasquet B Levi C Roux O Nekachtali O Baiges A Hernández-Gea V Laouénan C Lebrec D Albuquerque Miguel Paradis Valérie Moreau Richard Valla Dominique Durand François Boulanger CM Garcia-Pagan JC Rautou Pierre-Emmanuel

• Publication date : 08 July 2018 More

  NADPH oxidase depletion in neutrophils from patients with cirrhosis and restoration via toll-like receptor 7/8 activation

  Gut. 2018;67(8):1505-1516

  Authors : Rolas L Boussif A Weiss Emmanuel Letteron Philippe Haddad O El Benna Jamel Rautou Pierre-Emmanuel Moreau Richard Perianin Axel

• Publication date : 31 May 2018 More

  Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver

  Nat Commun.

  Authors : Hegde P Weiss Emmanuel Paradis Valérie Wan Jinghong Mabire Morgane Sukriti S Rautou Pierre-Emmanuel Albuquerque Miguel Picq O Gupta AC Ferrere G Gilgenkrantz Hélène Kiaf B Toubal A Beaudoin L Letteron Philippe Moreau Richard Lehuen A Lotersztajn Sophie

• Publication date : 03 January 2017 More

  Liver sinusoidal endothelial cells: physiology and role in liver diseases

  J Hepatol.

  Authors : Poisson Johanne Lemoinne S Boulanger C Durand François Moreau Richard Valla Dominique Rautou Pierre-Emmanuel

• Publication date : 03 May 2016 More

  Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome

  J Hepatol. 2017 May;66(5):930-941

  Authors : Weiss Emmanuel Rautou Pierre-Emmanuel Fasseu M Giabicani M De Chambrun M Wan Jinghong Minsart C Gustot Thierry Couvineau Alain Maiwall Hurtado-Nedelec Maria Margarita Pilard N Lebrec D Valla Dominique Durand François De La Grange P Monteiro Renato Paugam-Burtz Catherine Lotersztajn Sophie Moreau Richard

• Publication date : 30 April 2016 More

  Impaired intracellular signaling, myeloperoxidase release and bactericidal activity of neutrophils from patients with alcoholic cirrhosis

  J Hepatol.

  Authors : Abdelali Boussif Loïc Rolas Weiss Emmanuel Hamama Bouriche Moreau Richard Perianin Axel

• Publication date : 14 January 2016 More

  Hepatocyte Tissue Factor Contributes to the Hypercoagulable State in a Mouse Model of Chronic Liver Injury.

  J Hepatol.

  Authors : Rautou Pierre-Emmanuel Tatsumi K Antoniak S Owens AP Sparkenbaugh E Holle LA Wolberg AS Kopec AK Pawlinski R Luyendyk JP Mackman N Poisson Johanne Lemoinne S Boulanger C Durand François Moreau Richard Valla Dominique Rautou Pierre-Emmanuel

• Publication date : 31 January 2015 More

  Advanced fibrosis: correlation between pharmacokinetic parameters at dynamic gadoxetate-enhanced MR imaging and hepatocyte organic anion transporter expression in rat liver

  Radiology

  Authors : Lagadec M Doblas Sabrina Giraudeau C Ronot Maxime Lambert SA Fasseu M Paradis Valérie Moreau Richard Pastor CM Vilgrain Valérie Daire Jean-Luc Van Beers Bernard

• Publication date : 13 June 2014 More

  The emerging roles of microvesicles in liver diseases.

  Nat Rev Gastro Hepat

  Authors : Lemoinne S Thabut D Housset C Moreau Richard Valla Dominique Boulanger CM Rautou Pierre-Emmanuel

• Publication date : 05 March 2013 More

  Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis

  Gastroenterology.

  Authors : Moreau Richard Jalan R Gines P Pavesi M Angeli P Cordoba J Durand François Gustot Thierry Saliba F Domenicali M Gerbes A Wendon J Alessandria C Laleman W Zeuzem S Trebicka J Bernardi M Arroyo V CANONIC Study Investigators of the EASL–CLIF Consortium

• Publication date : 28 February 2013 More

  Inhibition of mammalian target of rapamycin aggravates the respiratory burst defect of neutrophils from decompensated patients with cirrhosis

  Hepatology.

  Authors : Loïc Rolas Nesrine Makhezer Soumeya Hadjoudj El Benna Jamel Bahia Djerdjouri Elkrief Laure Moreau Richard Perianin Axel

• Publication date : 29 March 2012 More

  Abnormal Plasma Microparticles Impair Vasoconstrictor Responses in Patients with Cirrhosis.

  Gastroenterology.

  Authors : Rautou Pierre-Emmanuel Bresson J Sainte-Marie Y Vion AC Paradis Valérie Renard JM Devue C Heymes C Letteron Philippe Elkrief Laure Lebrec D Valla Dominique Tedgui A Moreau Richard Boulanger CM

• Publication date : 31 August 2011 More

  Altered endoplasmic reticulum stress affects translation in inactive colon tissue from patients with ulcerative colitis

  Gastroenterology.

  Authors : Treton Xavier Pédruzzi E Cazals-Hatem Dominique Grodet A Panis Yves Groyer A Moreau Richard Bouhnik Yoram Daniel F Ogier-Denis Eric