Publications

• Publication date : 28 September 2025 More

  Predictive value of metabolic state on PanNET response to mTOR inhibitors

  Endocr Relat Cancer

  Authors : Cros Jérome Margot Bucau Matthieu Tihy Maxime Palazzo Pierre Bourgoin Anais Chassac Albuquerque Miguel Sauvanet Alain Dokmak Safi Dioguardi Burgio Marco Paradis Valérie Olivia Hentic Ruszniewski Philippe De Mestier Louis Rebours Vinciane Couvelard Anne

• Publication date : 09 April 2025 More

  Protective role of oleic acid against palmitic acid-induced pancreatic fibrosis

  J Transl Med.

  Authors : Frendi Sonia Anaïs Chassac Véron Killian Raffenne Jérome Nicolle Rémy Albuquerque Miguel Paradis Valérie Couvelard Anne Cros Jérome Rebours Vinciane

• Publication date : 10 February 2025 More

  Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom‐up approach

  J Pathol.

  Authors : Hilmi Marc Flore Delecourt Raffenne Jérome Bourega Taib Nelson Dusetti Juan Iovanna Yuna Blum Magali Richard Cindy Neuzillet Couvelard Anne Matthieu Tihy De Mestier Louis Rebours Vinciane Nicolle Rémy Cros Jérome

• Publication date : 18 March 2024 More

  Role of the fatty pancreatic infiltration in pancreatic oncogenesis

  Sci Rep.

  Authors : Frendi Sonia Chloé Martineau Cazier Hélène Nicolle Rémy Anaïs Chassac Albuquerque Miguel Raffenne Jérome Le Faouder Julie Paradis Valérie Cros Jérome Couvelard Anne Rebours Vinciane

• Publication date : 13 November 2023 More

  Prediction of Adjuvant Gemcitabine Sensitivity in Resectable Pancreatic Adenocarcinoma Using the GemPred RNA Signature: An Ancillary Study of the PRODIGE-24/CCTG PA6 Clinical Trial

  J Clin Oncol.

  Authors : Nicolle Rémy Jean-Baptiste Bachet Alexandre Harlé Juan Iovanna Hammel Pascal Rebours Vinciane Anthony Turpin Meher Ben Abdelghani Alice Wei Emmanuel Mitry Anthony Lopez James Biagi Eric François Pascal Artru Aurélien Lambert Daniel J Renouf Laure Monard Marjorie Mauduit Nelson Dusetti Thierry Conroy Cros Jérome

• Publication date : 12 June 2023 More

  Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of pancreatic adenocarcinoma

  Nat Commun.

  Authors : Charlie Saillard Flore Delecourt Benoit Schmauch Olivier Moindrot Magali Svrcek Armelle Bardier-Dupas Jean Francois Emile Mira Ayadi Rebours Vinciane De Mestier Louis Hammel Pascal Cindy Neuzillet Jean Baptiste Bachet Juan Iovanna Nelson Dusetti Yuna Blum Magali Richard Yasmina Kermezli Paradis Valérie Mikhail Zaslavskiy Pierre Courtiol Aurelie Kamoun Nicolle Rémy Cros Jérome

• Publication date : 31 August 2022 More

  Molecular deciphering of primary liver neuroendocrine neoplasms confirms their distinct existence with foregut-like profile

  J Pathol.

  Authors : De Mestier Louis Nicolle Rémy Poté Nicolas Rebours Vinciane Cauchy François Olivia Hentic Frédérique Maire Ronot Maxime Lebtahi Rachida Sauvanet Alain Paradis Valérie Ruszniewski Philippe Couvelard Anne Cros Jérome

• Publication date : 06 June 2022 More

  The Orexin-A/OX1R System Induces Cell Death in Pancreatic Cancer Cells Resistant to Gemcitabine and Nab-Paclitaxel Treatment

  Frontiers on Oncology

  Authors : Voisin Thierry Nicole Pascal Gratio Valérie Anaïs Chassac Dounia Mansour Rebours Vinciane Couvelard Anne Couvineau Alain

• Publication date : 10 March 2021 More

  Pancreatic Ductal Adenocarcinoma Arising in Young and Old Patients Displays Similar Molecular Features

  Cancers (Basel) .

  Authors : Raffenne Jérome Fernando A Martin Rémy Nicolle Marina Konta Yuna Blum Jérôme Torrisani Francesco Puleo Jean Baptiste Bachet Magali Svrcek Armel Bardier-Dupas Jean Francois Emile Peter Demetter Miroslav Radman Jean Luc Van Laethem Hammel Pascal Rebours Vinciane Paradis Valérie Couvelard Anne Cros Jérome

• Publication date : 01 October 2018 More

  Obesity-induced pancreatopathy in rats is reversible after bariatric surgery

  Sci Rep

  Authors : Rebours Vinciane Garteiser Philippe Ribeiro-Parenti Lara Cavin JB Doblas Sabrina Page Gwenael Bado André Couvineau Alain Ruszniewski Philippe Paradis Valérie Le Gall Maude Van Beers Bernard Couvelard Anne

• Publication date : 08 January 2018 More

  In vitro, in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma.

  Oncotarget.

  Authors : Dayot Stephanie Speisky D Couvelard Anne Bourgoin P Gratio Valérie Cros Jérome Rebours Vinciane Sauvanet Alain Bedossa Pierre Paradis Valérie Ruszniewski Philippe Couvineau Alain Voisin Thierry

• Publication date : 29 September 2013 More

  Hypoxia pathways and cellular stress activate pancreatic stellate cells: development of an organotypic culture model of thick slices of normal human pancreas

  PLoS One, 2013;8:e76229

  Authors : Rebours Vinciane Albuquerque Miguel Sauvanet Alain Ruszniewski Philippe Levy Philippe Paradis Valérie Bedossa Pierre Couvelard Anne