Publications

• Publication date : 06 October 2025 More

  Blockade of mTOR ameliorates IgA nephropathy by correcting CD89 and CD71 dysfunctions in humanized mice

  PLoS One.

  Authors : Cambier Alexandra Da silva Jennifer Bex-Coudrat Julie Canesi Fanny Lison Lachize Neanne Aurélie Sannier Hélène Mathieu Boedec Erwan Amandine Badie Monteiro Renato

• Publication date : 08 October 2024 More

  A new role for PI3Kγ in Fc receptor mediated cross-presentation

  Adv Sci (Weinh).

  Authors : Koumantou Despoina Aimé Cézaire Adiko Bourdely Pierre Nugue Mathilde Boedec Erwan El Benna Jamel Monteiro Renato Cosmin Saveanu Muriel Laffargue Matthias P Wymann Marc Dalod Guermonprez Pierre Saveanu Loredana

• Publication date : 08 October 2024 More

  Specific Requirement of the p84/p110γ Complex of PI3Kγ for Antibody‐Activated, Inducible Cross‐Presentation in Murine Type 2 DCs

  Adv Sci (Weinh).

  Authors : Koumantou Despoina Aimé Cézaire Adiko Bourdely Pierre Nugue Mathilde Boedec Erwan El Benna Jamel Monteiro Renato Cosmin Saveanu Muriel Laffargue Matthias P Wymann Marc Dalod Guermonprez Pierre Saveanu Loredana

• Publication date : 06 March 2024 More

  Identification of a Direct Role for Gut-Flora in Autoimmune Disease

  Sci Transl Med.

  Authors : Patrick J Gleeson Nicolas Benech Jonathan Chemouny Eleftheria Metallinou Laureline Berthelot Da silva Jennifer Bex-Coudrat Julie Boedec Erwan Fanny Canesi Bounaix Carine Willy Morelle Maryse Moya-Nilges John Kenny Liam O'Mahony Saveanu Loredana Bertrand Arnulf Aurélie Sannier Daugas Eric Vrtovsnik François Patricia Lepage Harry Sokol Monteiro Renato

• Publication date : 09 October 2023 More

  MAIT cells altered phenotype and cytotoxicity in lupus patients are linked to renal disease severity and outcome

  Front Immunol.

  Authors : Elena Litvinova Bounaix Carine Hanouna Guillaume Da silva Jennifer Laura Noailles Lucie Beaudoin Michael Padden Nessrine Bellamri Agnès Lehuen Daugas Eric Monteiro Renato Flament Heloise

• Publication date : 08 June 2023 More

  Activating FcγR function depends on endosomal-signaling platforms

  iScience.

  Authors : Benadda Samira Nugue Mathilde Koumantou Despoina Bens Marcelle Mariacristina De Luca Olivier Pellé Monteiro Renato Evnouchidou Irini Saveanu Loredana

• Publication date : 31 January 2022 More

  Soluble CD89 is a critical factor for mesangial proliferation in childhood IgA nephropathy

  Kidney Int.

  Authors : Cambier Alexandra Patrick J Gleeson Lilia Abbad Fanny Canesi Da silva Jennifer Bex-Coudrat Julie Deschenes Georges Olivia Boyer Marion Rabant Tim Ulinski Julien Hogan Michel Peuchmaur Laureline Berthelot Monteiro Renato

• Publication date : 31 December 2021 More

  Erythrocytosis associated with IgA nephropathy

  EBioMedicine.

  Authors : Cohen Camille Séverine Coulon Kanit Bhukhai Antoine Neuraz Michael Dussiot Guillemette Fouquet Le Stang Marie-Bénédicte Flamant Martin Vrtovsnik François Aurélie Hummel Bertrand Knebelmann Laurent Mesnard Eric Rondeau Thiago T Maciel Fabrizia Favale Nicole Casadevall Thao Nguyen-Khoa Stéphane Moutereau Christophe Legendre Benhamou Marc Monteiro Renato Olivier Hermine Khalil El Karoui Ivan C Moura

• Publication date : 29 September 2021 More

  Is complement the main accomplice in IgA nephropathy? From initial observations to potential complement-targeted therapies

  Mol Immunol.

  Authors : Le Stang Marie-Bénédicte Patrick J Gleeson Mohamed R Daha Monteiro Renato C van Kooten

• Publication date : 14 April 2020 More

  LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling.

  Sci Transl Med

  Authors : Wan Jinghong Weiss Emmanuel Ben Mkaddem Sanae Mabire Morgane Pierre-Marie Choinier Olivia Picq Tristan Thibault-Sogorb Pushpa Hegde Dorsa Pishvaie Bens Marcelle Linda Broer Gilgenkrantz Hélène Moreau Richard Saveanu Loredana Patrice Codogno Monteiro Renato Lotersztajn Sophie

• Publication date : 30 June 2019 More

  Modulation of the microbiota by oral antibiotics treats immunoglobulin A nephropathy in humanized mice.

  Nephrol Dial Transplant.

  Authors : Chemouny JM Gleeson PJ Abbad L Lauriero G Boedec Erwan Le Roux K Monot C Bredel M Bex-Coudrat Julie Sannier A Daugas Eric Vrtovsnik François Gesualdo L Leclerc M Berthelot L Ben Mkaddem Sanae Lepage P Monteiro Renato

• Publication date : 15 April 2019 More

  CD89 Is a Potent Innate Receptor for Bacteria and Mediates Host Protection from Sepsis.

  Cell Rep.

  Authors : De Tymowski Christian Heming N Correia MDT Abbad L Le Stang Marie-Bénédicte Flament Heloise Bex J Boedec Erwan Bounaix Carine Soler-Torronteras R Denamur E Galicier L Oksenhendler E Fehling HJ Pinheiro da Silva F Benhamou Marc Monteiro Renato Ben Mkaddem Sanae

• Publication date : 30 November 2017 More

  Serum Iron Protects from Renal Postischemic Injury.

  J Am Soc Nephrol.

  Authors : Vaugier C Amano MT Chemouny JM Dussiot M Berrou C Matignon M Ben Mkaddem Sanae Wang PHM Fricot A Maciel TT Grapton D Mathieu JRR Beaumont Carole Peraldi MN Peyssonnaux C Mesnard L Daugas Eric Vrtovsnik François Monteiro Renato Hermine O Ginzburg YZ Benhamou Marc Camara NOS Flamant Martin Moura IC

• Publication date : 14 August 2017 More

  Lyn and Fyn function as molecular switches that control antigen receptors directing homeostasis or inflammation

  Nat Comm, in press.

  Authors : Ben Mkaddem Sanae Murua Amaya Flament Heloise Titeca Dimitri Bounaix Carine Danelli Luca Launay Pierre Benhamou Marc Blank Ulrich Daugas Eric Nicolas Charles Monteiro Renato

• Publication date : 09 March 2017 More

  Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo

  PLoS One.

  Authors : Kassas-Guediri A Bex-Coudrat Julie Lebourdais-Pacreau Emeline Launay Pierre Monteiro Renato Blank Ulrich Nicolas Charles Benhamou Marc

• Publication date : 31 August 2016 More

  IgA1 Protease Treatment Reverses Mesangial Deposits and Hematuria in a Model of IgA Nephropathy.

  J Am Soc Nephrol.

  Authors : Lechner SM Abbad L Boedec Erwan Papista C Le Stang Marie-Bénédicte Moal C Maillard J Jamin A Bex-Coudrat Julie Wang Y Li A Martini PG Monteiro Renato Berthelot L.

• Publication date : 03 May 2016 More

  Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome

  J Hepatol. 2017 May;66(5):930-941

  Authors : Weiss Emmanuel Rautou Pierre-Emmanuel Fasseu M Giabicani M De Chambrun M Wan Jinghong Minsart C Gustot Thierry Couvineau Alain Maiwall Hurtado-Nedelec Maria Margarita Pilard N Lebrec D Valla Dominique Durand François De La Grange P Monteiro Renato Paugam-Burtz Catherine Lotersztajn Sophie Moreau Richard

• Publication date : 30 September 2015 More

  Recurrent IgA nephropathy is predicted by altered glycosylated IgA, autoantibodies and soluble CD89 complexes.

  Kidney Int.

  Authors : Berthelot L Robert T Vuiblet V Tabary T Braconnier A Dramé M Toupance O Rieu P Monteiro Renato Touré F

• Publication date : 31 July 2015 More

  Gluten exacerbates IgA nephropathy in humanized mice through gliadin-CD89 interaction.

  Kidney Int.

  Authors : Papista C Lechner S Le Stang Marie-Bénédicte Ben Mkaddem Sanae Bex-Coudrat Julie Pillebout Evangéline Chemouny J Jablonski M Flamant Martin Daugas Eric Vrtovsnik François Yiangou M Berthelot L Monteiro Renato

• Publication date : 24 July 2014 More

  Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis

  J Clin Invest.

  Authors : Ben Mkaddem Sanae Hayem G Jönsson F Rossato E Boedec Erwan Boussetta T El Benna Jamel Launay Pierre Goujon JM Benhamou Marc Bruhns P Monteiro Renato

• Publication date : 25 March 2012 More

  Transglutaminase is essential for IgA nephropathy development acting through IgA receptors

  J Exp Med.

  Authors : Berthelot L Papista C Maciel TT Biarnes-Pelicot M Tissandie E Wang PH Tamouza H Jamin A Bex-Coudrat Julie Gestin A Boumediene A Arcos-Fajardo M England P Pillebout Evangéline Walker Francine Daugas Eric Vrtosvnik F Flamant Martin Benhamou Marc Cogné M Moura IC Monteiro Renato

• Publication date : 13 February 2012 More

  IgG1 and IVIg induce inhibitory ITAM signaling through FcγRIII controlling inflammatory responses

  Blood. 2012, 119(13):3084-96

  Authors : Aloulou M Ben Mkaddem Sanae Biarnes-Pelicot M Boussetta T Souchet H Rossato E Benhamou Marc Crestani B Zhu Z Blank Ulrich Launay Pierre Monteiro Renato