Publications

• Publication date : 03 October 2025 More

  Silybum marianum seeds mitigate pro-inflammatory functions of human neutrophils and alleviate ulcerative colitis in rats

  Inflammopharmacology.

  Authors : Kouki Ahmed Riadh Marrouchi Abdelaziz Souli Salwa Bouabdallah Ferjani Wafa Dang Pham My-Chan Amadou Dicko El Benna Jamel Mossadok Ben-Attia

• Publication date : 24 July 2025 More

  Deciphering opsonized zymosan-induced phosphorylation of p47phox and NADPH oxidase activation in human neutrophils

  Blood.

  Authors : Liu Jie Pintard Coralie Thieblemont Nathalie Dang Pham My-Chan El Benna Jamel

• Publication date : 15 February 2025 More

  The protein tyrosine phosphatase Lyp/PTPN22 drives TNFα-induced priming of superoxide anions production by neutrophils and arthritis

  Free Radic Biol Med.

  Authors : Anaïs Gardette Viviana Marzaioli Bedouhene Samia Gilles Hayem Hurtado-Nedelec Maria Margarita Yantao He Dang Pham My-Chan Dieude Philippe Zhong-Yin Zhang Marie Jean-Claude El Benna Jamel

• Publication date : 04 October 2024 More

  Opuntia ficus-indica cladodes extract inhibits human neutrophil pro-inflammatory functions and protects rats from acetic acid-induced ulcerative colitis

  Inflammopharmacology.

  Authors : Wafa Ferjani Ahmed Kouki Dang Pham My-Chan Hamadi Fetoui Yassine Chtourou Néziha Ghanem-Boughanmi Mossadok Ben-Attia El Benna Jamel Abdelaziz Souli

• Publication date : 06 June 2024 More

  The peptidyl-prolyl isomerase Pin1 controls GM-CSF-induced priming of NADPH oxidase in human neutrophils and priming at inflammatory sites

  Int Immunopharmacol.

  Authors : Tarek Boussetta Houssam Raad Bedouhene Samia Arabi-Derkawi Riad Gougerot-Pocidalo Marie-Anne Gilles Hayem Dang Pham My-Chan El Benna Jamel

• Publication date : 19 September 2023 More

  TNFα counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes

  Redox Biol.

  Authors : Ben-Khemis Marwah Liu Dan Pintard Coralie Song Zhuoyao Hurtado-Nedelec Maria Margarita Marie Jean-Claude El Benna Jamel Dang Pham My-Chan

• Publication date : 16 January 2023 More

  ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes

  PNAS

  Authors : Asma Tlili Pintard Coralie Hurtado-Nedelec Maria Margarita Liu Dan Viviana Marzaioli Thieblemont Nathalie Dang Pham My-Chan El Benna Jamel

• Publication date : 01 January 2022 More

  Impaired p47phox phosphorylation in neutrophils from p67phox-deficient chronic granulomatous disease patients

  Blood.

  Authors : Sahra Amel Belambri Viviana Marzailoli Hurtado-Nedelec Maria Margarita Pintard Coralie Shiyu Liang Yezhou Liu Tarek Boussetta Gougerot-Pocidalo Marie-Anne Richard D Ye Dang Pham My-Chan El Benna Jamel

• Publication date : 28 January 2022 More

  Metformin Inhibits ROS Production by Human M2 Macrophages via the Activation of AMPK

  Biomedicines

  Authors : Rana M Nassif Elias Chalhoub Pia Chedid Hurtado-Nedelec Maria Margarita Elia Raya Dang Pham My-Chan Marie Jean-Claude El Benna Jamel

• Publication date : 10 January 2022 More

  Protein Kinase CK2 acts as a molecular brake to control NADPH oxidase 1 activation and colon inflammation

  Cell Mol Gastroenterol Hepatol.

  Authors : Liu Dan Marie Jean-Claude Pelletier Anne-Laure Song Zhuoyao Ben-Khemis Marwah Kaouthar Boudiaf Pintard Coralie Thibaut Leger Samuel Terrier Guillaume Chevreux El Benna Jamel Dang Pham My-Chan

• Publication date : 31 August 2021 More

  Prolyl-Isomerase Pin1 Controls Key fMLP-Induced Neutrophil Functions

  Biomedicines

  Authors : Bedouhene Samia Liu Min Nassima Senani Tarek Boussetta Pintard Coralie Dang Pham My-Chan El Benna Jamel

• Publication date : 02 August 2020 More

  The protein kinase A negatively regulates reactive oxygen species production by phosphorylating gp91phox/NOX2 in human neutrophils

  Free Radic Biol Med

  Authors : Houssam Raad Hussein Mouawia Hamad Hassan Mohamed El-Seblani Riad Arabi-Derkawi Tarek Boussetta Gougerot-Pocidalo Marie-Anne Dang Pham My-Chan El Benna Jamel

• Publication date : 30 June 2020 More

  Apocynin prevents GM-CSF-induced-ERK1/2 activation and -neutrophil survival independently of its inhibitory effect on the phagocyte NADPH oxidase NOX2

  Biochem Pharmacol.

  Authors : Pintard Coralie Ben-Khemis Marwah Liu Dan Dang Pham My-Chan Hurtado-Nedelec Maria Margarita El Benna Jamel

• Publication date : 21 January 2020 More

  The dual role of ROS-generating NADPH oxidases in gastrointestinal inflammation and therapeutic perspectives.

  Antioxidants & Redox Signaling.

  Authors : Dang Pham My-Chan Rolas L El Benna Jamel

• Publication date : 31 October 2019 More

  The prolyl isomerase Pin1 controls lipopolysaccharide-induced priming of NADPH oxidase in human neutrophils.

  Frontiers In Immunology.

  Authors : Liu Min Bedouhene Samia Hurtado-Nedelec Maria Margarita Pintard Coralie Dang Pham My-Chan Yu S El Benna Jamel

• Publication date : 05 September 2019 More

  Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.

  J Exp Med.

  Authors : Ohayon D De Chiara A Dang Pham My-Chan Thieblemont N Chatfield S Marzaioli V Burgener SS Mocek J Candalh C Pintard Coralie Tacnet-Delorme P Renault G Lagoutte I Favier M Walker Francine Hurtado-Nedelec Maria Margarita Desplancq D Weiss Emmanuel Benarafa C Housset D Marie Jean-Claude Frachet P El Benna Jamel Witko-Sarsat V

• Publication date : 28 February 2019 More

  The Kinesin Light Chain-Related Protein PAT1 Promotes Superoxide Anion Production in Human Phagocytes.

  J Immunol.

  Authors : Arabi-Derkawi R O'Dowd Y Cheng N Rolas L Boussetta T Raad H Marzaioli V Pintard Coralie Fasseu M Kroviarski Y Belambri SA Dang Pham My-Chan Ye RD Gougerot-Pocidalo Marie-Anne El Benna Jamel

• Publication date : 01 September 2018 More

  NOX1-derived ROS drive the expression of Lipocalin-2 in colonic epithelial cells in inflammatory conditions

  Mucosal Immunology.

  Authors : Makhezer N Ben-Khemis Marwah Liu Dan Khichane Y Marzaioli V Tlili A Mojallali Marjan Pintard Coralie Letteron Philippe Hurtado-Nedelec Maria Margarita El Benna Jamel Marie Jean-Claude Sannier A Pelletier Anne-Laure Dang Pham My-Chan

• Publication date : 11 October 2017 More

  NOX5 and p22phox are 2 novel regulators of human monocytic differentiation into dendritic cells.

  Blood. 2017 Oct 12;130(15):1734-1745

  Authors : Marzaioli V Hurtado-Nedelec Maria Margarita Pintard Coralie Tlili A Marie Jean-Claude Monteiro RC Gougerot-Pocidalo Marie-Anne Dang Pham My-Chan El Benna Jamel

• Publication date : 28 February 2017 More

  Vasoactive intestinal peptide dampens formyl-peptide-induced ROS production and inflammation by targeting a MAPK-p47(phox) phosphorylation pathway in monocytes

  Mucosal Immunology, 2017 Mar;10(2):332-340

  Authors : Chedid P Boussetta T Dang Pham My-Chan Belambri SA Marzaioli V, Fasseau M Walker Francine Couvineau Alain El Benna Jamel Marie Jean-Claude

• Publication date : 13 September 2016 More

  Priming of the neutrophil respiratory burst : Role in host defense and inflammation

  Immunological Reviews, 2016 Sep;273(1):180-93

  Authors : El-Benna J Hurtado-Nedelec Maria Margarita Marzaioli M Marie Jean-Claude Gougerot-Pocidalo Marie-Anne Dang Pham My-Chan

• Publication date : 30 June 2012 More

  Towards specific NADPH oxidase inhibition by small synthetic peptides

  Cell Mol Life Sci.

  Authors : El Benna Jamel Dang Pham My-Chan Perianin Axel

• Publication date : 22 December 2010 More

  The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils.

  Blood. 2010 Dec 23;116(26):5795-802

  Authors : Boussetta T Gougerot-Pocidalo Marie-Anne Hayem G Ciappelloni S Raad H Arabi Derkawi R Bournier O Kroviarski Y Zhou XZ Malter JS Lu PK Bartegi A Dang Pham My-Chan El Benna Jamel