Publications

• Publication date : 21 February 2025 More

  Altered liver sinusoidal endothelial cells in MASLD and their evolution following lanifibranor treatment

  JHEP Rep.

  Authors : Rautou Pierre-Emmanuel Shivani Chotkoe Biquard Louise Guillaume Wettstein Denise van der Graaff Yao Liu Joris De Man Christophe Casteleyn Sofie Thys Winnok H De Vos Bedossa Pierre Michael P Cooreman Martine Baudin Jean-Louis Abitbol Philippe Huot-Marchand Lucile Dzen Albuquerque Miguel Pierre Broqua Jean-Louis Junien Luisa Vonghia Manal F Abdelmalek Wilhelmus J Kwanten Paradis Valérie Sven M Francque

• Publication date : 16 February 2025 More

  Altered liver sinusoidal endothelial cells in MASLD and their evolution following lanifibranor treatment

  JHEP Reports

  Authors : Rautou Pierre-Emmanuel Shivani Chotkoe Biquard Louise Guillaume Wettstein Denise Van der Graaff Yao Liu Joris De Man Christophe Casteleyn Sofie Thys Winnok H. De Vos Bedossa Pierre Michael P. Cooreman Martine Baudin JeanLouis Abitbol Philippe Huot-Marchand Lucile Dzen Albuquerque Miguel Pierre Broqua Jean-Louis Junien Luisa Vonghia Manal F. Abdelmalek Wilhelmus J. Kwanten Paradis Valérie Sven M. Francque

• Publication date : 29 September 2021 More

  Prospective comparison of transient elastography, MRI and serum scores for grading steatosis and detecting non-alcoholic steatohepatitis in bariatric surgery candidates

  JHEP Rep.

  Authors : Garteiser Philippe Castera Laurent Coupaye Muriel Doblas Sabrina Calabrese Daniela Dioguardi Burgio Marco Ledoux Séverine Bedossa Pierre Marina Esposito-Farèse Msika Simon Van Beers Bernard Pauline Jouët

• Publication date : 12 January 2020 More

  The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma

  Liver Int.

  Authors : Poté Nicolas Cros Jérome Laouirem Samira Raffenne Jérome Negrão M Albuquerque Miguel Bedossa Pierre Godinho Ferreira M Ait Si Ali S Fior R Paradis Valérie

• Publication date : 31 March 2019 More

  Endothelial fatty liver binding protein 4: a new targetable mediator in hepatocellular carcinoma related to metabolic syndrome.

  Oncogene.

  Authors : Laouirem Samira Sannier A Norkowski E Cauchy F Doblas Sabrina Rautou Pierre-Emmanuel Albuquerque Miguel Garteiser Philippe Sognigbé L Raffenne Jérome Van Beers Bernard Soubrane Olivier Bedossa Pierre Cros Jérome Paradis Valérie

• Publication date : 31 March 2018 More

  Contribution of virtual biopsy to the screening of microvascular invasion in hepatocellular carcinoma: A pilot study

  Liver Int.

  Authors : Poté Nicolas Cauchy François Albuquerque Miguel Cros Jérome Soubrane Olivier Bedossa Pierre Paradis Valérie

• Publication date : 08 January 2018 More

  In vitro, in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma.

  Oncotarget.

  Authors : Dayot Stephanie Speisky D Couvelard Anne Bourgoin P Gratio Valérie Cros Jérome Rebours Vinciane Sauvanet Alain Bedossa Pierre Paradis Valérie Ruszniewski Philippe Couvineau Alain Voisin Thierry

• Publication date : 01 July 2017 More

  Plasma cytokeratin-18 fragments are an accurate non-invasive tool for the diagnosis of severe alcoholic hepatitis

  Hepatology. 2017 Aug; 66(2):555-563

  Authors : Bissonnette J Altamirano J Devue C Roux O Payance A Lebrec D Bedossa Pierre Valla Dominique Durand François Ait-Oufella H Sancho-Bru P Caballeria J Boulanger CM Bataller R Rautou Pierre-Emmanuel

• Publication date : 31 July 2017 More

  A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis.

  Hepatology.

  Authors : Bissonnette J Altamirano J Devue C Roux O Payancé A Lebrec D Bedossa Pierre Valla Dominique Durand François Ait-Oufella H Sancho-Bru P Caballeria J Ginès P Boulanger CM Bataller R Rautou Pierre-Emmanuel

• Publication date : 14 November 2016 More

  Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression

  Gut. 2016 Nov;65(11):1882-1894

  Authors : Loyer X Paradis Valérie Hénique C Vion AC Colnot N Guerin CL Devue C On S Scetbun J Romain M Paul JL Rothenberg ME Marcellin Patrick Durand François Bedossa Pierre Prip-Buus C Baugé E Staels B Boulanger CM Tedgui A Rautou Pierre-Emmanuel

• Publication date : 11 October 2016 More

  MicroRNA-based diagnostic tools for advanced fibrosis and cirrhosis in patients with chronic hepatitis B and C

  Scientific Reports

  Authors : Kevin Appourchaux Dokmak Safi Matthieu Resche-Rigon Treton Xavier Martine Lapalus Charles-Henry Gattolliat Emmanuelle Porchet Michelle Martinot-Peignoux Boyer Nathalie Michel Vidaud Bedossa Pierre Marcellin Patrick Ivan Bièche Emilie Estrabaud Asselah Tarik

• Publication date : 29 February 2016 More

  Heterozygous Mutations in BMP6 Pro-peptide Lead to Inappropriate Hepcidin Synthesis and Moderate Iron Overload in Humans.

  Gastroenterology.

  Authors : Daher Raed Kannengiesser Caroline Houamel D Lefebvre Thibaud Bardou-Jacquet E Ducrot Nicolas De Kerguenec C Jouanolle AM Robreau AM Oudin C Le Gac C Moulouel Boualem Loustaud-Ratti V Bedossa Pierre Valla Dominique Gouya Laurent Beaumont Carole Brissot P Puy Hervé Tchernitchko Dimitri

• Publication date : 31 May 2014 More

  Reduction of MicroRNA 122 Expression in IFNL3 CT/TT Carriers and during Progression of Fibrosis in Patients with Chronic Hepatitis C

  J Virol

  Authors : Estrabaud E Lapalus M Broët P Appourchaux K Muynck SD Lada O Martinot-Peignoux M Bièche I Valla Dominique Bedossa Pierre Marcellin Patrick Vidaud M Asselah Tarik

• Publication date : 09 October 2013 More

  IFNL3 (IL28B) polymorphism does not predict long-term response to interferon therapy in HBeAg-positive chronic hepatitis B patients

  J Viral Hepat, 2013 Oct 10. doi: 10.1111/jvh.12177

  Authors : Zhang Q Lapalus M Asselah Tarik Laouénan C Moucari R Martinot-Peignoux M Bieche I Estrabaud E De Muynck S Boyer Nathalie Bedossa Pierre Vidaud M Marcellin Patrick Lada O

• Publication date : 29 September 2013 More

  Hypoxia pathways and cellular stress activate pancreatic stellate cells: development of an organotypic culture model of thick slices of normal human pancreas

  PLoS One, 2013;8:e76229

  Authors : Rebours Vinciane Albuquerque Miguel Sauvanet Alain Ruszniewski Philippe Levy Philippe Paradis Valérie Bedossa Pierre Couvelard Anne

• Publication date : 29 July 2013 More

  Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas

  Hepatology, 2013;58:983-94

  Authors : Poté Nicolas Alexandrov T Le Faouder Julie Laouirem Samira Léger T Mebarki M Belghiti Jacques Camadro JM Bedossa Pierre Paradis Valérie

• Publication date : 31 August 2012 More

  Cullin7: a new gene involved in liver carcinogenesis related to metabolic syndrome

  Gut, 2013;62:911-9.

  Authors : Paradis Valérie Albuquerque Miguel Mebarki M Hernandez L Zalinski S Quentin S Belghiti Jacques Soulier J Bedossa Pierre

• Publication date : 10 September 2011 More

  IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C

  J Hepatol, 2011. 56(3): p. 527-32

  Authors : Asselah Tarik De Muynck S Broet P Masliah-Planchon J Blanluet M Bieche I Lapalus M Martinot-Peignoux M Lada O Estrabaud E Zhang Q El Ray A Vidaud D Ripault MP Boyer Nathalie Bedossa Pierre Valla Dominique Vidaud M Marcellin Patrick

• Publication date : 30 April 2011 More

  Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis

  Cancer Res

  Authors : Voisin Thierry El Firar A Fasseu M Rouyer-Fessard C Descatoire V Walker Francine Paradis Valérie Bedossa Pierre Henin D Lehy T Laburthe M