Publications

• Publication date : 01 April 2025 More

  Immune characterization of lupus nephritis patients undergoing dialysis

  J Transl Autoimmun.

  Authors : Simon Quentin Gaillard François Tchen John Delphine Bachelet Sacre Karim Katell Peoc'h Noémie Jourde-Chiche Daugas Eric Charles Nicolas

• Publication date : 21 April 2024 More

  PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus

  Nature Communications

  Authors : Tchen John Simon Quentin Chapart Lea Thaminy Morgane Vibhushan Shamila Saveanu Loredana Lamri Yasmine Saidoune Fanny Lebourdais-Pacreau Emeline Pellefigues Christophe Bex-Coudrat Julie Hajime KARASUYAMA Kensuke MIYAKE Juan HIDALGO Padraic G. FALLON Papo Thomas Blank Ulrich Benhamou Marc Hanouna Guillaume Sacre Karim Daugas Eric Charles Nicolas

• Publication date : 06 March 2024 More

  Identification of a Direct Role for Gut-Flora in Autoimmune Disease

  Sci Transl Med.

  Authors : Patrick J Gleeson Nicolas Benech Jonathan Chemouny Eleftheria Metallinou Laureline Berthelot Da silva Jennifer Bex-Coudrat Julie Boedec Erwan Fanny Canesi Bounaix Carine Willy Morelle Maryse Moya-Nilges John Kenny Liam O'Mahony Saveanu Loredana Bertrand Arnulf Aurélie Sannier Daugas Eric Vrtovsnik François Patricia Lepage Harry Sokol Monteiro Renato

• Publication date : 09 October 2023 More

  MAIT cells altered phenotype and cytotoxicity in lupus patients are linked to renal disease severity and outcome

  Front Immunol.

  Authors : Elena Litvinova Bounaix Carine Hanouna Guillaume Da silva Jennifer Laura Noailles Lucie Beaudoin Michael Padden Nessrine Bellamri Agnès Lehuen Daugas Eric Monteiro Renato Flament Heloise

• Publication date : 10 January 2023 More

  Pathogenic accumulation of T follicular helper cells in lupus disease depends on PD-L1 and IL-4 expressing basophils

  medRxiv

  Authors : Tchen John Simon Quentin Chapart Lea Lamri Yasmine Saidoune Fanny Lebourdais-Pacreau Emeline Pellefigues Christophe Bex-Coudrat Julie Karasuyama H Miyake K Hidalgo J Fallon PG Papo Thomas Blank Ulrich Benhamou Marc Hanouna Guillaume Sacre Karim Daugas Eric Charles Nicolas

• Publication date : 30 September 2022 More

  Weaning of maintenance immunosuppressive therapy in lupus nephritis (WIN-Lupus): results of a multicentre randomised controlled trial

  Ann Rheum Dis.

  Authors : Noemie Jourde-Chiche Nathalie Costedoat-Chalumeau Karine Baumstarck Anderson Loundou Laurence Bouillet Stéphane Burtey Valérie Caudwell Laurent Chiche Lionel Couzi Laurent Daniel Christophe Deligny Bertrand Dussol Stanislas Faguer Pierre Gobert Guillaume Gondran Antoine Huart Aurélie Hummel Emilie Kalbacher Adexandre Karra Marc Lambert Véronique Le Guern Ludivine Lebourg Sandrine Loubière Hélène Maillard-Lefebvre François Maurier Micheline Pha Viviane Queyrel Philippe Remy Françoise Sarrot-Reynauld David Verhelst Eric Hachulla Zahir Amoura Daugas Eric WIN-Lupus study group

• Publication date : 28 June 2022 More

  CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development

  Front Immunol.

  Authors : Tchen John Simon Quentin Chapart Lea Pellefigues Christophe Hajime Karasuyama Kensuke Miyake Blank Ulrich Benhamou Marc Daugas Eric Charles Nicolas

• Publication date : 01 November 2021 More

  CD62L on blood basophils: a first pre-treatment predictor of remission in severe lupus nephritis

  Nephrol Dial Transplant.

  Authors : Matthieu Halfon Delphine Bachelet Hanouna Guillaume Barbara Dema Pellefigues Christophe Pauline Manchon Cedric Laouenan Charles Nicolas Daugas Eric

• Publication date : 31 March 2021 More

  Basophils and IgE contribute to mixed connective tissue disease development

  J Allergy Clin Immunol.

  Authors : Lamri Yasmine Vibhushan Shamila Lebourdais-Pacreau Emeline Boedec Erwan Saidoune Fanny Arnaud Mailleux Bruno Crestani Blank Ulrich Benhamou Marc Papo Thomas Daugas Eric Sacre Karim Charles Nicolas

• Publication date : 29 December 2020 More

  Mast Cell Chymase and Kidney Disease

  International Journal of Molecular Sciences

  Authors : Vibhushan Shamila Bratti Manuela Juan Eduardo Montero-Hernández Alaa El Ghoneimi Benhamou Marc Charles Nicolas Daugas Eric Blank Ulrich

• Publication date : 29 February 2020 More

  Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment

  Kidney Int.

  Authors : Lydia Celia Madjene Luca Danelli Albert Dahdah Vibhushan Shamila Bex-Coudrat Julie Lebourdais-Pacreau Emeline Celine Vaugier Julien Claver Loïc Rolas Maguelonne Pons Iris Karina Madera-Salcedo Walid Beghdadi El Ghoneimi Alaa Benhamou Marc Launay Pierre Magnus Abrink Gunnar Pejler Ivan Cruz Moura Charles Nicolas Daugas Eric Perianin Axel Blank Ulrich

• Publication date : 30 June 2019 More

  Modulation of the microbiota by oral antibiotics treats immunoglobulin A nephropathy in humanized mice.

  Nephrol Dial Transplant.

  Authors : Chemouny JM Gleeson PJ Abbad L Lauriero G Boedec Erwan Le Roux K Monot C Bredel M Bex-Coudrat Julie Sannier A Daugas Eric Vrtovsnik François Gesualdo L Leclerc M Berthelot L Ben Mkaddem Sanae Lepage P Monteiro Renato

• Publication date : 30 April 2019 More

  Basophil involvement in lupus nephritis: a basis for innovation in daily care

  Nephrol Dial Transplant.

  Authors : Charles Nicolas Jonathan M Chemouny Daugas Eric

• Publication date : 19 February 2018 More

  Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs

  Nat Commun.

  Authors : Pellefigues Christophe Dema B Lamri Yasmine Saidoune Fanny Lohéac C Lebourdais-Pacreau Emeline Dussiot M Bidault C Marquet F Jablonski M Chemouny JM Jouan F Dossier A Chauveheid MP Gobert D Papo Thomas Karasuyama H Sacre Karim Daugas Eric Charles Nicolas

• Publication date : 30 November 2017 More

  Serum Iron Protects from Renal Postischemic Injury.

  J Am Soc Nephrol.

  Authors : Vaugier C Amano MT Chemouny JM Dussiot M Berrou C Matignon M Ben Mkaddem Sanae Wang PHM Fricot A Maciel TT Grapton D Mathieu JRR Beaumont Carole Peraldi MN Peyssonnaux C Mesnard L Daugas Eric Vrtovsnik François Monteiro Renato Hermine O Ginzburg YZ Benhamou Marc Camara NOS Flamant Martin Moura IC

• Publication date : 14 August 2017 More

  Lyn and Fyn function as molecular switches that control antigen receptors directing homeostasis or inflammation

  Nat Comm, in press.

  Authors : Ben Mkaddem Sanae Murua Amaya Flament Heloise Titeca Dimitri Bounaix Carine Danelli Luca Launay Pierre Benhamou Marc Blank Ulrich Daugas Eric Charles Nicolas Monteiro Renato

• Publication date : 10 August 2017 More

  Basophils contribute to pristane-induced Lupus-like nephritis model

  Sci Rep.

  Authors : Barbara Dema Lamri Yasmine Pellefigues Christophe Lebourdais-Pacreau Emeline Saidoune Fanny Caroline Bidault Hajime Karasuyama Sacre Karim Daugas Eric Charles Nicolas

• Publication date : 14 March 2017 More

  Early Phase Mast Cell Activation Determines the Chronic Outcome of Renal Ischemia-Reperfusion Injury

  J Immunol.

  Authors : Danelli L Madjene LC Madera-Salcedo I Gautier Gregory Lebourdais-Pacreau Emeline Ben Mkaddem Sanae Charles Nicolas Daugas Eric Launay Pierre Blank Ulrich

• Publication date : 31 July 2015 More

  Gluten exacerbates IgA nephropathy in humanized mice through gliadin-CD89 interaction.

  Kidney Int.

  Authors : Papista C Lechner S Le Stang Marie-Bénédicte Ben Mkaddem Sanae Bex-Coudrat Julie Pillebout Evangéline Chemouny J Jablonski M Flamant Martin Daugas Eric Vrtovsnik François Yiangou M Berthelot L Monteiro Renato

• Publication date : 25 March 2012 More

  Transglutaminase is essential for IgA nephropathy development acting through IgA receptors

  J Exp Med.

  Authors : Berthelot L Papista C Maciel TT Biarnes-Pelicot M Tissandie E Wang PH Tamouza H Jamin A Bex-Coudrat Julie Gestin A Boumediene A Arcos-Fajardo M England P Pillebout Evangéline Walker Francine Daugas Eric Vrtosvnik F Flamant Martin Benhamou Marc Cogné M Moura IC Monteiro Renato