Publications

• Publication date : 01 April 2025 More

  Immune characterization of lupus nephritis patients undergoing dialysis

  J Transl Autoimmun.

  Authors : Simon Quentin Gaillard François Tchen John Delphine Bachelet Sacre Karim Katell Peoc'h Noémie Jourde-Chiche Daugas Eric Charles Nicolas

• Publication date : 21 April 2024 More

  PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus

  Nature Communications

  Authors : Tchen John Simon Quentin Chapart Lea Thaminy Morgane Vibhushan Shamila Saveanu Loredana Lamri Yasmine Saidoune Fanny Lebourdais-Pacreau Emeline Pellefigues Christophe Bex-Coudrat Julie Hajime KARASUYAMA Kensuke MIYAKE Juan HIDALGO Padraic G. FALLON Papo Thomas Blank Ulrich Benhamou Marc Hanouna Guillaume Sacre Karim Daugas Eric Charles Nicolas

• Publication date : 08 August 2023 More

  Autoreactive IgE: Pathogenic role and therapeutic target in autoimmune diseases

  Allergy.

  Authors : Charles Nicolas Inge Kortekaas-Krohn Emek Kocaturk Jörg Scheffel Sabine Altrichter Carolin Steinert Yi-Kui Xiang Jan Gutermuth Laurent L Reber Marcus Maurer

• Publication date : 10 January 2023 More

  Pathogenic accumulation of T follicular helper cells in lupus disease depends on PD-L1 and IL-4 expressing basophils

  medRxiv

  Authors : Tchen John Simon Quentin Chapart Lea Lamri Yasmine Saidoune Fanny Lebourdais-Pacreau Emeline Pellefigues Christophe Bex-Coudrat Julie Karasuyama H Miyake K Hidalgo J Fallon PG Papo Thomas Blank Ulrich Benhamou Marc Hanouna Guillaume Sacre Karim Daugas Eric Charles Nicolas

• Publication date : 31 December 2022 More

  Impact of BNT162b2 mRNA anti-SARS-CoV-2 vaccine on interferon-alpha production by plasmacytoid dendritic cells and autoreactive T cells in patients with systemic lupus erythematosus: The COVALUS project

  J Autoimmun.

  Authors : Mageau Arthur Tchen John Valentine Marie Ferré Pascale Nicaise-Roland Diane Descamps Nicole Delory Chrystelle François Celine Mendes Papo Thomas Tiphaine Goulenok Charles Nicolas Sacre Karim

• Publication date : 30 June 2022 More

  Systemic lupus erythematosus flare following SARS-CoV2 infection: the implication of IFNα and anti-IFNα autoantibodies

  Clin Exp Rheumatol.

  Authors : Mageau Arthur Pascale Nicaise Roland Tiphaine Goulenok Carine Farkh Charles Nicolas Sacre Karim

• Publication date : 28 June 2022 More

  CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development

  Front Immunol.

  Authors : Tchen John Simon Quentin Chapart Lea Pellefigues Christophe Hajime Karasuyama Kensuke Miyake Blank Ulrich Benhamou Marc Daugas Eric Charles Nicolas

• Publication date : 03 April 2022 More

  AMG853, A Bispecific Prostaglandin D2 Receptor 1 and 2 Antagonist, Dampens Basophil Activation and Related Lupus-Like Nephritis Activity in Lyn-Deficient Mice

  Front Immunol.

  Authors : Pellefigues Christophe Tchen John Chaimae Saji Lamri Yasmine Charles Nicolas

• Publication date : 31 March 2022 More

  Basophils and IgE in autoimmunity: Mechanisms and therapeutic targets

  Med Sci (Paris).

  Authors : Tchen John Charles Nicolas

• Publication date : 01 November 2021 More

  CD62L on blood basophils: a first pre-treatment predictor of remission in severe lupus nephritis

  Nephrol Dial Transplant.

  Authors : Matthieu Halfon Delphine Bachelet Hanouna Guillaume Barbara Dema Pellefigues Christophe Pauline Manchon Cedric Laouenan Charles Nicolas Daugas Eric

• Publication date : 30 September 2021 More

  Autoimmunity, IgE and FcεRI-bearing cells

  Curr Opin Immunol.

  Authors : Charles Nicolas

• Publication date : 31 March 2021 More

  Basophils and IgE contribute to mixed connective tissue disease development

  J Allergy Clin Immunol.

  Authors : Lamri Yasmine Vibhushan Shamila Lebourdais-Pacreau Emeline Boedec Erwan Saidoune Fanny Arnaud Mailleux Bruno Crestani Blank Ulrich Benhamou Marc Papo Thomas Daugas Eric Sacre Karim Charles Nicolas

• Publication date : 31 January 2021 More

  Effects of BAFF Neutralization on Atherosclerosis Associated With Systemic Lupus Erythematosus

  Arthritis Rheumatol.

  Authors : Saidoune Fanny Guillaume Even Lamri Yasmine Julie Chezel Anh-Thu Gaston Brigitte Escoubet Papo Thomas Charles Nicolas Antonino Nicoletti Sacre Karim

• Publication date : 29 December 2020 More

  Mast Cell Chymase and Kidney Disease

  International Journal of Molecular Sciences

  Authors : Vibhushan Shamila Bratti Manuela Juan Eduardo Montero-Hernández Alaa El Ghoneimi Benhamou Marc Charles Nicolas Daugas Eric Blank Ulrich

• Publication date : 07 December 2020 More

  IgE in the Pathogenesis of SLE: From Pathogenic Role to Therapeutic Target

  Antibodies (Basel).

  Authors : Lamri Yasmine Charles Nicolas

• Publication date : 29 February 2020 More

  Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment

  Kidney Int.

  Authors : Lydia Celia Madjene Luca Danelli Albert Dahdah Vibhushan Shamila Bex-Coudrat Julie Lebourdais-Pacreau Emeline Celine Vaugier Julien Claver Loïc Rolas Maguelonne Pons Iris Karina Madera-Salcedo Walid Beghdadi El Ghoneimi Alaa Benhamou Marc Launay Pierre Magnus Abrink Gunnar Pejler Ivan Cruz Moura Charles Nicolas Daugas Eric Perianin Axel Blank Ulrich

• Publication date : 30 April 2019 More

  Basophil involvement in lupus nephritis: a basis for innovation in daily care

  Nephrol Dial Transplant.

  Authors : Charles Nicolas Jonathan M Chemouny Daugas Eric

• Publication date : 19 November 2018 More

  Mast Cell Degranulation Exacerbates Skin Rejection by Enhancing Neutrophil Recruitment

  Front Immunol.

  Authors : Ngo Nyekel Flavie Lebourdais-Pacreau Emeline Benadda Samira Msallam Rasha Åbrink Magnus Pejler Gunnar Davoust Jean Benhamou Marc Charles Nicolas Launay Pierre Blank Ulrich Gautier Gregory

• Publication date : 02 July 2018 More

  Tomosyn functions as a PKCδ-regulated fusion clamp in mast cell degranulation

  Sci Signal.

  Authors : Madera-Salcedo IK Danelli L Tiwari N Dema N Lebourdais-Pacreau Emeline Vibhushan Shamila Birnbaum J Agabriel C Liabeuf V Klingebiel C Menasche G Macias-Silva M Benhamou Marc Charles Nicolas González-Espinosa C Vitte J Blank Ulrich

• Publication date : 19 February 2018 More

  Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs

  Nat Commun.

  Authors : Pellefigues Christophe Dema B Lamri Yasmine Saidoune Fanny Lohéac C Lebourdais-Pacreau Emeline Dussiot M Bidault C Marquet F Jablonski M Chemouny JM Jouan F Dossier A Chauveheid MP Gobert D Papo Thomas Karasuyama H Sacre Karim Daugas Eric Charles Nicolas

• Publication date : 14 August 2017 More

  Lyn and Fyn function as molecular switches that control antigen receptors directing homeostasis or inflammation

  Nat Comm, in press.

  Authors : Ben Mkaddem Sanae Murua Amaya Flament Heloise Titeca Dimitri Bounaix Carine Danelli Luca Launay Pierre Benhamou Marc Blank Ulrich Daugas Eric Charles Nicolas Monteiro Renato

• Publication date : 10 August 2017 More

  Basophils contribute to pristane-induced Lupus-like nephritis model

  Sci Rep.

  Authors : Barbara Dema Lamri Yasmine Pellefigues Christophe Lebourdais-Pacreau Emeline Saidoune Fanny Caroline Bidault Hajime Karasuyama Sacre Karim Daugas Eric Charles Nicolas

• Publication date : 14 March 2017 More

  Early Phase Mast Cell Activation Determines the Chronic Outcome of Renal Ischemia-Reperfusion Injury

  J Immunol.

  Authors : Danelli L Madjene LC Madera-Salcedo I Gautier Gregory Lebourdais-Pacreau Emeline Ben Mkaddem Sanae Charles Nicolas Daugas Eric Launay Pierre Blank Ulrich

• Publication date : 09 March 2017 More

  Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo

  PLoS One.

  Authors : Kassas-Guediri A Bex-Coudrat Julie Lebourdais-Pacreau Emeline Launay Pierre Monteiro Renato Blank Ulrich Charles Nicolas Benhamou Marc