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    • Scientific axes
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      • Technical Platform of Ussing Chambers
      • qPCR Technical Platform
      • E-Cell Therapy facility
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Quick access

  • Our scientific axes
    • Pathophysiology of inflammatory & fibrotic diseases axis
    • Oncogenic inflammation & tumor development axis
    • Immunology, Signaling and Cellular Dynamics
  • Instances
    • Council of the Center
    • Support committee for doctoral students (CDS)
    • Representatives of doctoral students
    • Mediation and Quality of Life Committee at CRI (CMQVC)
  • Sustainable development

Our Teams

  • Asselah
  • Charles
  • Dang / Hurtado Nedelec
  • De Chaisemartin / Launay
  • Cohen
  • Helou
  • Haumaitre / Cros
  • Garteiser / Van Beers
  • Le Gall
  • Mailleux / Crestani
  • Rémy Nicolle
  • Rautou
  • Saveanu
  • Sinkus
  • Viennois / Meinzer
  • Weiss / Gilgenkrantz

  • Research
  • Training
  • Platforms
  • Employment / internships

  • Useful information

 

Accueil / Charles / Sacre Karim

Sacre Karim

University Professor - Hospital Practitioner (PUPH) /

 
  • Scientific axis : Immunology, Signaling and Cellular Dynamics
  • Team : Charles
  • Fonction : Researcher(s)
  • karim.sacre@aphp.fr
 
 

Publications

  • Publication date : 01 April 2025 More

    Immune characterization of lupus nephritis patients undergoing dialysis
    J Transl Autoimmun.

    Authors : Simon Quentin Gaillard François Tchen John Delphine Bachelet Sacre Karim Katell Peoc'h Noémie Jourde-Chiche Daugas Eric Charles Nicolas

  • Publication date : 21 April 2024 More

    PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus
    Nature Communications

    Authors : Tchen John Simon Quentin Chapart Lea Thaminy Morgane Vibhushan Shamila Saveanu Loredana Lamri Yasmine Saidoune Fanny Lebourdais-Pacreau Emeline Pellefigues Christophe Bex-Coudrat Julie Hajime KARASUYAMA Kensuke MIYAKE Juan HIDALGO Padraic G. FALLON Papo Thomas Blank Ulrich Benhamou Marc Hanouna Guillaume Sacre Karim Daugas Eric Charles Nicolas

  • Publication date : 10 January 2023 More

    Pathogenic accumulation of T follicular helper cells in lupus disease depends on PD-L1 and IL-4 expressing basophils
    medRxiv

    Authors : Tchen John Simon Quentin Chapart Lea Lamri Yasmine Saidoune Fanny Lebourdais-Pacreau Emeline Pellefigues Christophe Bex-Coudrat Julie Karasuyama H Miyake K Hidalgo J Fallon PG Papo Thomas Blank Ulrich Benhamou Marc Hanouna Guillaume Sacre Karim Daugas Eric Charles Nicolas

  • Publication date : 31 December 2022 More

    Impact of BNT162b2 mRNA anti-SARS-CoV-2 vaccine on interferon-alpha production by plasmacytoid dendritic cells and autoreactive T cells in patients with systemic lupus erythematosus: The COVALUS project
    J Autoimmun.

    Authors : Mageau Arthur Tchen John Valentine Marie Ferré Pascale Nicaise-Roland Diane Descamps Nicole Delory Chrystelle François Celine Mendes Papo Thomas Tiphaine Goulenok Charles Nicolas Sacre Karim

  • Publication date : 30 June 2022 More

    Systemic lupus erythematosus flare following SARS-CoV2 infection: the implication of IFNα and anti-IFNα autoantibodies
    Clin Exp Rheumatol.

    Authors : Mageau Arthur Pascale Nicaise Roland Tiphaine Goulenok Carine Farkh Charles Nicolas Sacre Karim

  • Publication date : 30 December 2021 More

    Acute myocarditis revealing autoimmune and inflammatory disorders: Clinical presentation and outcome
    Int J Cardiol.

    Authors : Camille Chaligne Mageau Arthur Gregory Ducrocq Phalla Ou Jean-Francois Alexandra Pierre Mutuon Papo Thomas Sacre Karim

  • Publication date : 31 July 2021 More

    SARS-CoV-2 infection among inpatients with systemic lupus erythematosus in France: a nationwide epidemiological study
    Ann Rheum Dis.

    Authors : Mageau Arthur Geoffrey Aldebert Damien Van Gysel Papo Thomas Jean-François Timsit Sacre Karim

  • Publication date : 31 March 2021 More

    Basophils and IgE contribute to mixed connective tissue disease development
    J Allergy Clin Immunol.

    Authors : Lamri Yasmine Vibhushan Shamila Lebourdais-Pacreau Emeline Boedec Erwan Saidoune Fanny Arnaud Mailleux Bruno Crestani Blank Ulrich Benhamou Marc Papo Thomas Daugas Eric Sacre Karim Charles Nicolas

  • Publication date : 31 January 2021 More

    Effects of BAFF Neutralization on Atherosclerosis Associated With Systemic Lupus Erythematosus
    Arthritis Rheumatol.

    Authors : Saidoune Fanny Guillaume Even Lamri Yasmine Julie Chezel Anh-Thu Gaston Brigitte Escoubet Papo Thomas Charles Nicolas Antonino Nicoletti Sacre Karim

  • Publication date : 19 February 2018 More

    Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs
    Nat Commun.

    Authors : Pellefigues Christophe Dema B Lamri Yasmine Saidoune Fanny Lohéac C Lebourdais-Pacreau Emeline Dussiot M Bidault C Marquet F Jablonski M Chemouny JM Jouan F Dossier A Chauveheid MP Gobert D Papo Thomas Karasuyama H Sacre Karim Daugas Eric Charles Nicolas

  • Publication date : 10 August 2017 More

    Basophils contribute to pristane-induced Lupus-like nephritis model
    Sci Rep.

    Authors : Barbara Dema Lamri Yasmine Pellefigues Christophe Lebourdais-Pacreau Emeline Saidoune Fanny Caroline Bidault Hajime Karasuyama Sacre Karim Daugas Eric Charles Nicolas

 
 

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Actuality

  • The CRI participated in Odyssea


  • Congratulations to Georges Doumet Helou for winning the Sanofi iAwards Europe


  • Congratulations to Marie Robert, winner of the L’Oréal-Unesco For Women in Science Award!



  • List of new arrivals

Les dernières publications marquantes

  • Publication date : 06 October 2025 More

    Blockade of mTOR ameliorates IgA nephropathy by correcting CD89 and CD71 dysfunctions in humanized mice
    PLoS One.

    Authors : Cambier Alexandra Da silva Jennifer Bex-Coudrat Julie Canesi Fanny Lison Lachize Neanne Aurélie Sannier Hélène Mathieu Boedec Erwan Amandine Badie Monteiro Renato

  • Publication date : 03 October 2025 More

    Silybum marianum seeds mitigate pro-inflammatory functions of human neutrophils and alleviate ulcerative colitis in rats
    Inflammopharmacology.

    Authors : Kouki Ahmed Riadh Marrouchi Abdelaziz Souli Salwa Bouabdallah Ferjani Wafa Dang Pham My-Chan Amadou Dicko El Benna Jamel Mossadok Ben-Attia

  • Publication date : 28 September 2025 More

    Predictive value of metabolic state on PanNET response to mTOR inhibitors
    Endocr Relat Cancer

    Authors : Cros Jérome Margot Bucau Matthieu Tihy Maxime Palazzo Pierre Bourgoin Anais Chassac Albuquerque Miguel Sauvanet Alain Dokmak Safi Dioguardi Burgio Marco Paradis Valérie Olivia Hentic Ruszniewski Philippe De Mestier Louis Rebours Vinciane Couvelard Anne


  • CRI Publications

 
 

Center for Inflammation Research

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ERL CNRS 8252

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16 rue Henri Huchard F-75018 Paris

 
 
 
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