Publications

• Publication date : 28 September 2025 More

  Predictive value of metabolic state on PanNET response to mTOR inhibitors

  Endocr Relat Cancer

  Authors : Cros Jérome Margot Bucau Matthieu Tihy Maxime Palazzo Pierre Bourgoin Anais Chassac Albuquerque Miguel Sauvanet Alain Dokmak Safi Dioguardi Burgio Marco Paradis Valérie Olivia Hentic Ruszniewski Philippe De Mestier Louis Rebours Vinciane Couvelard Anne

• Publication date : 09 April 2025 More

  Protective role of oleic acid against palmitic acid-induced pancreatic fibrosis

  J Transl Med.

  Authors : Frendi Sonia Anaïs Chassac Véron Killian Raffenne Jérome Nicolle Rémy Albuquerque Miguel Paradis Valérie Couvelard Anne Cros Jérome Rebours Vinciane

• Publication date : 21 February 2025 More

  Altered liver sinusoidal endothelial cells in MASLD and their evolution following lanifibranor treatment

  JHEP Rep.

  Authors : Rautou Pierre-Emmanuel Shivani Chotkoe Biquard Louise Guillaume Wettstein Denise van der Graaff Yao Liu Joris De Man Christophe Casteleyn Sofie Thys Winnok H De Vos Bedossa Pierre Michael P Cooreman Martine Baudin Jean-Louis Abitbol Philippe Huot-Marchand Lucile Dzen Albuquerque Miguel Pierre Broqua Jean-Louis Junien Luisa Vonghia Manal F Abdelmalek Wilhelmus J Kwanten Paradis Valérie Sven M Francque

• Publication date : 16 February 2025 More

  Altered liver sinusoidal endothelial cells in MASLD and their evolution following lanifibranor treatment

  JHEP Reports

  Authors : Rautou Pierre-Emmanuel Shivani Chotkoe Biquard Louise Guillaume Wettstein Denise Van der Graaff Yao Liu Joris De Man Christophe Casteleyn Sofie Thys Winnok H. De Vos Bedossa Pierre Michael P. Cooreman Martine Baudin JeanLouis Abitbol Philippe Huot-Marchand Lucile Dzen Albuquerque Miguel Pierre Broqua Jean-Louis Junien Luisa Vonghia Manal F. Abdelmalek Wilhelmus J. Kwanten Paradis Valérie Sven M. Francque

• Publication date : 05 September 2024 More

  Prognostic impact of the tumour microenvironment in intrahepatic cholangiocarcinoma: identification of a peritumoural fibro-immune interface

  Virchows Arch.

  Authors : Gwladys Lubuela Beaufrère Aurélie Albuquerque Miguel Camille Pignollet Nicolle Rémy Lesurtel Mickaël Bouattour Mohamed Cros Jérome Paradis Valérie

• Publication date : 18 March 2024 More

  Role of the fatty pancreatic infiltration in pancreatic oncogenesis

  Sci Rep.

  Authors : Frendi Sonia Chloé Martineau Cazier Hélène Nicolle Rémy Anaïs Chassac Albuquerque Miguel Raffenne Jérome Le Faouder Julie Paradis Valérie Cros Jérome Couvelard Anne Rebours Vinciane

• Publication date : 30 September 2023 More

  Pathological overview of steatohepatitic hepatocellular carcinoma in a surgical series

  Histopathology.

  Authors : Loïc Trapani Beaufrère Aurélie Christian Hobeika Tatiana Codjia Albuquerque Miguel Mohamed Bouattour Lesurtel Mickaël Cauchy François Paradis Valérie

• Publication date : 11 July 2023 More

  A new NRF2 activator for the treatment of human metabolic dysfunction-associated fatty liver disease

  JHEP Rep.

  Authors : Hammoutene Adel Laouirem Samira Albuquerque Miguel Nathalie Colnot Brzustowski Angelique Valla Dominique Nicolas Provost Philippe Delerive Paradis Valérie QUID-NASH Research Group

• Publication date : 31 March 2023 More

  MALDI Imaging, a Powerful Multiplex Approach to Decipher Intratumoral Heterogeneity: Combined Hepato-Cholangiocarcinomas as Proof of Concept

  Cancers.

  Authors : Elia Gigante Cazier Hélène Albuquerque Miguel Laouirem Samira Beaufrère Aurélie Paradis Valérie

• Publication date : 31 October 2022 More

  The Appendix Orchestrates T-Cell Mediated Immunosurveillance in Colitis-Associated Cancer

  Cell Mol Gastroenterol Hepatol.

  Authors : Collard Maxime Tourneur--Marsille Julien Mathieu Uzzan Albuquerque Miguel Roy Maryline Dumay Anne Jean-Noël Freund Hugot Jean-Pierre Guedj Nathalie Treton Xavier Panis Yves Ogier-Denis Eric

• Publication date : 30 June 2021 More

  Transarterial chemoembolisation enhances programmed death-1 and programmed death-ligand 1 expression in hepatocellular carcinoma

  Histopathology.

  Authors : Ahmed Montasser Beaufrère Aurélie Cauchy François Mohamed Bouattour Soubrane Olivier Albuquerque Miguel Paradis Valérie

• Publication date : 27 August 2020 More

  Prognostic value of desmoplastic stroma in intrahepatic cholangiocarcinoma

  Modern Pathology.

  Authors : Guedj Nathalie Lorraine Blaise Cauchy François Albuquerque Miguel Soubrane Olivier Paradis Valérie

• Publication date : 09 April 2020 More

  Immune-checkpoint inhibitor anti-PD1 aggravates colitis-associated colorectal cancer without enhancing intestinal inflammation

  Integrative Cancer Science and Therapeutics

  Authors : Collard Maxime Guedj Nathalie Tourneur--Marsille Julien Albuquerque Miguel Maggiori Leon Hammel Pascal Treton Xavier Panis Yves Ogier-Denis Eric

• Publication date : 12 January 2020 More

  The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma

  Liver Int.

  Authors : Poté Nicolas Cros Jérome Laouirem Samira Raffenne Jérome Negrão M Albuquerque Miguel Bedossa Pierre Godinho Ferreira M Ait Si Ali S Fior R Paradis Valérie

• Publication date : 31 March 2019 More

  Endothelial fatty liver binding protein 4: a new targetable mediator in hepatocellular carcinoma related to metabolic syndrome.

  Oncogene.

  Authors : Laouirem Samira Sannier A Norkowski E Cauchy F Doblas Sabrina Rautou Pierre-Emmanuel Albuquerque Miguel Garteiser Philippe Sognigbé L Raffenne Jérome Van Beers Bernard Soubrane Olivier Bedossa Pierre Cros Jérome Paradis Valérie

• Publication date : 31 December 2018 More

  Proteomic Landscape of Cholangiocarcinomas Reveals Three Different Subgroups According to Their Localization and the Aspect of Non-Tumor Liver.

  Proteomics Clin Appl.

  Authors : Le Faouder Julie Gigante E Léger T Albuquerque Miguel Beaufrère A Soubrane Olivier Dokmak S Camadro JM Cros Jérome Paradis Valérie

• Publication date : 30 September 2018 More

  Hepatocyte microvesicle levels improve prediction of mortality in patients with cirrhosis.

  Hepatology

  Authors : Payancé A Silva-Junior G Bissonnette J Tanguy Marion Pasquet B Levi C Roux O Nekachtali O Baiges A Hernández-Gea V Laouénan C Lebrec D Albuquerque Miguel Paradis Valérie Moreau Richard Valla Dominique Durand François Boulanger CM Garcia-Pagan JC Rautou Pierre-Emmanuel

• Publication date : 31 May 2018 More

  Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver

  Nat Commun.

  Authors : Hegde P Weiss Emmanuel Paradis Valérie Wan Jinghong Mabire Morgane Sukriti S Rautou Pierre-Emmanuel Albuquerque Miguel Picq O Gupta AC Ferrere G Gilgenkrantz Hélène Kiaf B Toubal A Beaudoin L Letteron Philippe Moreau Richard Lehuen A Lotersztajn Sophie

• Publication date : 31 March 2018 More

  Contribution of virtual biopsy to the screening of microvascular invasion in hepatocellular carcinoma: A pilot study

  Liver Int.

  Authors : Poté Nicolas Cauchy François Albuquerque Miguel Cros Jérome Soubrane Olivier Bedossa Pierre Paradis Valérie

• Publication date : 09 April 2014 More

  Viscoelastic parameters for quantifying liver fibrosis: three-dimensional multifrequency MR elastography study on thin liver rat slices

  PLOS One, 2014;9(4):e94679

  Authors : Ronot Maxime Lambert SA Wagner M Garteiser Philippe Doblas Sabrina Albuquerque Miguel Paradis Valérie Vilgrain Valérie Sinkus R Van Beers Bernard

• Publication date : 29 September 2013 More

  Hypoxia pathways and cellular stress activate pancreatic stellate cells: development of an organotypic culture model of thick slices of normal human pancreas

  PLoS One, 2013;8:e76229

  Authors : Rebours Vinciane Albuquerque Miguel Sauvanet Alain Ruszniewski Philippe Levy Philippe Paradis Valérie Bedossa Pierre Couvelard Anne

• Publication date : 31 August 2012 More

  Cullin7: a new gene involved in liver carcinogenesis related to metabolic syndrome

  Gut, 2013;62:911-9.

  Authors : Paradis Valérie Albuquerque Miguel Mebarki M Hernandez L Zalinski S Quentin S Belghiti Jacques Soulier J Bedossa Pierre