Publications

• Publication date : 23 April 2025 More

  Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation

  Nature Communications

  Authors : Al Sayegh Rola Wan Jinghong Caër Charles Azoulai Margot Maxime Gasperment Sukriti Baweja Marc-Anthony Chouillard Kandiah Janany Cadoux Mathilde Mabire Morgane Pignolet Camille Tristan Thibault-Sogorb Hammoutene Adel Paradis Valérie Saveanu Loredana Nicolle Rémy Gilgenkrantz Hélène Weiss Emmanuel Lotersztajn Sophie

• Publication date : 15 May 2023 More

  Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration

  JHEP Rep.

  Authors : Allaire Manon Al Sayegh Rola Mabire Morgane Hammoutene Adel Matthieu Siebert Caër Charles Cadoux Mathilde Wan Jinghong Habib Aida Le Gall Maude Pierre de la Grange Hervé Guillou Catherine Postic Paradis Valérie Lotersztajn Sophie Gilgenkrantz Hélène

• Publication date : 31 March 2023 More

  MAIT cell inhibition promotes liver fibrosis regression via macrophage phenotype reprogramming

  Nature Commun.

  Authors : Mabire Morgane Pushpa Hegde Hammoutene Adel Wan Jinghong Caër Charles Al Sayegh Rola Cadoux Mathilde Weiss Emmanuel Tristan Thibault-Sogorb Olivier Lantz Michèle Goodhardt Paradis Valérie Pierre de la Grange Gilgenkrantz Hélène Lotersztajn Sophie

• Publication date : 14 April 2020 More

  LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling.

  Sci Transl Med

  Authors : Wan Jinghong Weiss Emmanuel Ben Mkaddem Sanae Mabire Morgane Pierre-Marie Choinier Olivia Picq Tristan Thibault-Sogorb Pushpa Hegde Dorsa Pishvaie Bens Marcelle Linda Broer Gilgenkrantz Hélène Moreau Richard Saveanu Loredana Patrice Codogno Monteiro Renato Lotersztajn Sophie

• Publication date : 31 March 2019 More

  In vitro distinction between proinflammatory and antiinflammatory macrophages with gadolinium-liposomes and ultrasmall superparamagnetic iron oxide particles at 3.0T

  J Magn Reson Imaging

  Authors : Khaled W Piraquive J Leporq B Wan Jinghong Lambert SA Mignet N Doan BT Lotersztajn Sophie Garteiser Philippe Van Beers Bernard

• Publication date : 08 October 2018 More

  Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

  Gut. 2018

  Authors : Habib Aida Chokr D Wan Jinghong Hegde P Mabire Morgane Siebert M Ribeiro-Parenti Lara Le Gall Maude Letteron Philippe Pilard N Mansouri Abdellah Brouillet A Tardelli M Weiss Emmanuel Le Faouder P Guillou H Cravatt BF Moreau Richard Trauner M Lotersztajn Sophie

• Publication date : 31 May 2018 More

  Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver

  Nat Commun.

  Authors : Hegde P Weiss Emmanuel Paradis Valérie Wan Jinghong Mabire Morgane Sukriti S Rautou Pierre-Emmanuel Albuquerque Miguel Picq O Gupta AC Ferrere G Gilgenkrantz Hélène Kiaf B Toubal A Beaudoin L Letteron Philippe Moreau Richard Lehuen A Lotersztajn Sophie

• Publication date : 03 May 2016 More

  Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome

  J Hepatol. 2017 May;66(5):930-941

  Authors : Weiss Emmanuel Rautou Pierre-Emmanuel Fasseu M Giabicani M De Chambrun M Wan Jinghong Minsart C Gustot Thierry Couvineau Alain Maiwall Hurtado-Nedelec Maria Margarita Pilard N Lebrec D Valla Dominique Durand François De La Grange P Monteiro Renato Paugam-Burtz Catherine Lotersztajn Sophie Moreau Richard

• Publication date : 13 August 2015 More

  Macrophage autophagy protects against liver fibrosis in mice.

  Autophagy. 2015;11(8):1280-92.

  Authors : Lodder J Denaës T Chobert MN Wan Jinghong El Benna Jamel Pawlotsky JM Lotersztajn Sophie Teixeira-Clerc F

• Publication date : 05 January 2014 More

  M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease

  Hepatology. 2014 Jan;59(1):130-42

  Authors : Wan Jinghong Benkdane M Teixeira-Clerc F Bonnafous S Louvet A Lafdil F Pecker F Tran A Gual A Mallat A Lotersztajn Sophie Pavoine C