{"id":80843,"date":"2026-03-11T13:57:00","date_gmt":"2026-03-11T14:57:00","guid":{"rendered":"https:\/\/cri1149.fr\/?post_type=publication&#038;p=80843"},"modified":"2026-03-11T15:59:48","modified_gmt":"2026-03-11T16:59:48","slug":"imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma","status":"publish","type":"publication","link":"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/","title":{"rendered":"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p><strong>Objectives:&nbsp;<\/strong>The aim of this study was to describe the imaging features on dynamic CT and MRI of a series of pathologically confirmed low-grade vascular neoplasia of the liver (LGVNL).<\/p>\n\n\n\n<p><strong>Materials and methods:&nbsp;<\/strong>In this retrospective multicenter study, patients diagnosed with pathologically proven LGVNL between January 2014 and August 2024 and with cross-sectional imaging (CT or MRI) were included. Based on prior studies, we divided the patients into two groups: a group with typical LGVNL features and a group with atypical tumors. Univariable analysis and the logistic regression model were used to evaluate the outcome of typical and atypical LGVNL features.<\/p>\n\n\n\n<p><strong>Results:&nbsp;<\/strong>Twenty-eight patients were included (20 men, mean age 53.7 \u00b1 13.4 [SD] years old). The median size of tumors at diagnosis was 22 mm [IQR, 10-80]. A typical LGVNL pattern including thick continuous peripheral arterial phase &#8220;flower petal shape&#8221; enhancement was found on MRI in 67% (18\/27) with lobulated lesions (p = 0.001), a marked hypersignal on T2-weighted images (p = 0.003) and a high apparent diffusion coefficient (ADC) (mean tumor ADC, 2.1 \u00d7 10<sup>-3<\/sup>&nbsp;\u00b1 0.3 [SD] mm<sup>2<\/sup>\/s) (p = 0.006) with portal and delayed phase filling following contrast administration. An atypical LGVNL pattern was found in 33% (9\/27), including homogeneous arterial phase enhancement that persisted during the portal and delayed phases. After a median follow-up of 16 months, tumor growth was observed in 42% (8\/19) and was faster in patients with the atypical LGVNL pattern (p = 0.013).<\/p>\n\n\n\n<p><strong>Conclusion:&nbsp;<\/strong>The typical imaging pattern of LGVNL that includes arterial phase &#8220;flower petal shape&#8221; enhancement with a marked hypersignal on T2-weighted images and a high ADC was seen in most cases.<\/p>\n\n\n\n<p><strong>Key points:&nbsp;<\/strong>Question Low-grade vascular neoplasia of the liver, including hepatic small vessel neoplasms and anastomosing hemangioma, is a new entity of vascular tumors with few radiological descriptions. Findings Diagnostic imaging criteria include the &#8220;flower petal shape&#8221; enhancement pattern on arterial phase, a marked hypersignal on T2-weighted images and high ADC values. Clinical relevance This multicenter study provides clinical, pathological and imaging data on low-grade vascular neoplasia of the liver and highlights specific imaging features for its diagnosis. Knowledge of these imaging features helps eliminate differential diagnoses.<\/p>\n\n\n\n<p><strong>Keywords:&nbsp;<\/strong>Diagnostic imaging; Liver neoplasms; Magnetic resonance imaging; Vascular neoplasms.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":true,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false},"category_publication":[],"class_list":["post-80843","publication","type-publication","status-publish","hentry"],"acf":{"numero_de_publication":"Eur Radiol.","date_de_publication":"20260228","numero_doi":"10.1007\/s00330-025-11915-4.","equipe":[335],"auteurs-liste":[{"texte_libre":true,"auteur-lien":null,"auteur-text":"Ma\u00eft\u00e9 Lewin"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Rauda Aldhaheri"},{"texte_libre":false,"auteur-lien":63210,"auteur-text":""},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Christophe Desterke"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Anita Paisant"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Ivan Bricault"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Paul Borde"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Gabriel Simon"},{"texte_libre":false,"auteur-lien":71742,"auteur-text":""},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Daniel Cherqui"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Clara Prud'Homme"},{"texte_libre":false,"auteur-lien":13166,"auteur-text":""},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Astrid Laurent-Bellue"}],"auteurs-manuel":"","liens_externes":[{"url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/40906183\/"}],"liens":null,"paragraphe":"","paragraphe_en":"","documents":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma - CRI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma - CRI\" \/>\n<meta property=\"og:description\" content=\"Abstract Objectives:&nbsp;The aim of this study was to describe the imaging features on dynamic CT and MRI of a series of pathologically confirmed low-grade vascular neoplasia of the liver (LGVNL). [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/\" \/>\n<meta property=\"og:site_name\" content=\"CRI\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/CRI-Centre-de-recherche-sur-linflammation-100116118884153\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-11T16:59:48+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/\",\"url\":\"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/\",\"name\":\"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma - CRI\",\"isPartOf\":{\"@id\":\"https:\/\/cri1149.fr\/#website\"},\"datePublished\":\"2026-03-11T14:57:00+00:00\",\"dateModified\":\"2026-03-11T16:59:48+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/cri1149.fr\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Publications\",\"item\":\"https:\/\/cri1149.fr\/publications\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/cri1149.fr\/#website\",\"url\":\"https:\/\/cri1149.fr\/\",\"name\":\"CRI - Centre de Recherche sur l'Inflammation\",\"description\":\"Centre de Recherche sur l&#039;Inflammation\",\"publisher\":{\"@id\":\"https:\/\/cri1149.fr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/cri1149.fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/cri1149.fr\/#organization\",\"name\":\"CRI1149\",\"url\":\"https:\/\/cri1149.fr\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/cri1149.fr\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/cri1149.fr\/wp-content\/uploads\/2014\/11\/8.4.2014-logo-CRI.jpg\",\"contentUrl\":\"https:\/\/cri1149.fr\/wp-content\/uploads\/2014\/11\/8.4.2014-logo-CRI.jpg\",\"width\":215,\"height\":176,\"caption\":\"CRI1149\"},\"image\":{\"@id\":\"https:\/\/cri1149.fr\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/CRI-Centre-de-recherche-sur-linflammation-100116118884153\",\"https:\/\/www.linkedin.com\/company\/cri-centre-de-recherche-sur-l-inflammation\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma - CRI","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/","og_locale":"en_US","og_type":"article","og_title":"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma - CRI","og_description":"Abstract Objectives:&nbsp;The aim of this study was to describe the imaging features on dynamic CT and MRI of a series of pathologically confirmed low-grade vascular neoplasia of the liver (LGVNL). [&hellip;]","og_url":"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/","og_site_name":"CRI","article_publisher":"https:\/\/www.facebook.com\/CRI-Centre-de-recherche-sur-linflammation-100116118884153","article_modified_time":"2026-03-11T16:59:48+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/","url":"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/","name":"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma - CRI","isPartOf":{"@id":"https:\/\/cri1149.fr\/#website"},"datePublished":"2026-03-11T14:57:00+00:00","dateModified":"2026-03-11T16:59:48+00:00","breadcrumb":{"@id":"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/cri1149.fr\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/cri1149.fr\/en\/"},{"@type":"ListItem","position":2,"name":"Publications","item":"https:\/\/cri1149.fr\/publications\/"},{"@type":"ListItem","position":3,"name":"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma"}]},{"@type":"WebSite","@id":"https:\/\/cri1149.fr\/#website","url":"https:\/\/cri1149.fr\/","name":"CRI - Centre de Recherche sur l'Inflammation","description":"Centre de Recherche sur l&#039;Inflammation","publisher":{"@id":"https:\/\/cri1149.fr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cri1149.fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/cri1149.fr\/#organization","name":"CRI1149","url":"https:\/\/cri1149.fr\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/cri1149.fr\/#\/schema\/logo\/image\/","url":"https:\/\/cri1149.fr\/wp-content\/uploads\/2014\/11\/8.4.2014-logo-CRI.jpg","contentUrl":"https:\/\/cri1149.fr\/wp-content\/uploads\/2014\/11\/8.4.2014-logo-CRI.jpg","width":215,"height":176,"caption":"CRI1149"},"image":{"@id":"https:\/\/cri1149.fr\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/CRI-Centre-de-recherche-sur-linflammation-100116118884153","https:\/\/www.linkedin.com\/company\/cri-centre-de-recherche-sur-l-inflammation\/"]}]}},"_links":{"self":[{"href":"https:\/\/cri1149.fr\/en\/wp-json\/wp\/v2\/publication\/80843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cri1149.fr\/en\/wp-json\/wp\/v2\/publication"}],"about":[{"href":"https:\/\/cri1149.fr\/en\/wp-json\/wp\/v2\/types\/publication"}],"acf:term":[{"embeddable":true,"taxonomy":"equipes","href":"https:\/\/cri1149.fr\/en\/wp-json\/wp\/v2\/equipes\/335"}],"wp:attachment":[{"href":"https:\/\/cri1149.fr\/en\/wp-json\/wp\/v2\/media?parent=80843"}],"wp:term":[{"taxonomy":"category_publication","embeddable":true,"href":"https:\/\/cri1149.fr\/en\/wp-json\/wp\/v2\/category_publication?post=80843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}