{"id":80486,"date":"2023-03-30T12:04:14","date_gmt":"2023-03-30T12:04:14","guid":{"rendered":"https:\/\/cri1149.fr\/publication\/evaluation-of-transcranial-doppler-use-in-patients-with-acute-liver-failure-listed-for-emergency-liver-transplantation\/"},"modified":"2023-03-30T12:04:14","modified_gmt":"2023-03-30T12:04:14","slug":"evaluation-of-transcranial-doppler-use-in-patients-with-acute-liver-failure-listed-for-emergency-liver-transplantation","status":"publish","type":"publication","link":"https:\/\/cri1149.fr\/en\/publication\/evaluation-of-transcranial-doppler-use-in-patients-with-acute-liver-failure-listed-for-emergency-liver-transplantation\/","title":{"rendered":"Evaluation of transcranial Doppler use in patients with acute liver failure listed for emergency liver transplantation"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false},"category_publication":[],"class_list":["post-80486","publication","type-publication","status-publish","hentry"],"acf":{"numero_de_publication":"Clin Transplant.","date_de_publication":"20230324","numero_doi":"","equipe":[391],"auteurs-liste":[{"texte_libre":true,"auteur-lien":null,"auteur-text":"Benjamin Picard"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"St\u00e9phanie Sigaut"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Olivier Roux"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Pa\u00ebr-Selim Abback"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Pierre-Marie Choinier"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Marina Hachouf"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Mikhael Giabicani "},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Juliette Kavafyan"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Claire Francoz"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Federica Dondero"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Micka\u00ebl Lesurtel"},{"texte_libre":false,"auteur-lien":13069,"auteur-text":""},{"texte_libre":false,"auteur-lien":63209,"auteur-text":""},{"texte_libre":false,"auteur-lien":13137,"auteur-text":""},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Souhayl Dahmani"},{"texte_libre":false,"auteur-lien":13172,"auteur-text":""}],"auteurs-manuel":"","liens_externes":[{"url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/36964926\/"}],"liens":[{"lien":""}],"paragraphe":"<h2 class=\"title\" style=\"text-align: justify;\">Abstract<\/h2>\n<div id=\"eng-abstract\" class=\"abstract-content selected\">\n<p style=\"text-align: justify;\"><strong class=\"sub-title\">Purpose: <\/strong>Acute liver failure (ALF) is characterized by hepatic encephalopathy (HE) often due to intracranial hypertension (ICH). The risk\/benefit-balance of intraparenchymal pressure catheter monitoring is controversial during ALF. <\/p>\n<p style=\"text-align: justify;\"><strong class=\"sub-title\">Aims: <\/strong>Perform an evaluation of transcranial Doppler (TCD) use in patients with ALF listed for emergency liver transplantation.<\/p>\n<p style=\"text-align: justify;\"><strong class=\"sub-title\">Material and methods: <\/strong>Single center retrospective cohort study including all patients registered on high emergency LT list between 2012 and 2018. All TCD measurements performed during ICU stay after listing and after LT (when performed) were recorded. TCD was considered abnormal when pulsatility index (PI) was >1.2.  <\/p>\n<p style=\"text-align: justify;\"><strong class=\"sub-title\">Results: <\/strong>Among 106 patients with ALF, forty-seven (44%) had a TCD while on list. They had more severe liver and extrahepatic organ failure. When performed, TCD was abnormal in 51% of patients. These patients more frequently developed ICH events (45% vs. 13%, p = .02) and more frequently required increase in sedative drugs and vasopressors. While 22% of patients with normal TCD spontaneously survived, all of those with abnormal TCD died or were transplanted (p = .02). All transplanted patients who had abnormal exams normalized their TCD within 2 (1-2) days after LT.     <\/p>\n<p style=\"text-align: justify;\"><strong class=\"sub-title\">Conclusion: <\/strong>TCD may be a useful non-invasive tool for ICH detection and management, then guide sedation withdrawal.<\/p>\n\n<\/div>","paragraphe_en":"","documents":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Evaluation of transcranial Doppler use in patients with acute liver failure listed for emergency liver transplantation - CRI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cri1149.fr\/publication\/evaluation-of-transcranial-doppler-use-in-patients-with-acute-liver-failure-listed-for-emergency-liver-transplantation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Evaluation of transcranial Doppler use in patients with acute liver failure listed for emergency liver transplantation - 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