{"id":15816,"date":"2020-08-20T15:40:34","date_gmt":"2020-08-20T13:40:34","guid":{"rendered":"https:\/\/cri1149.fr\/?post_type=publications&#038;p=15816"},"modified":"2025-09-11T16:48:01","modified_gmt":"2025-09-11T14:48:01","slug":"treatment-of-hepatitis-c-virus-infection-with-direct-acting-antiviral-agents-100-cure","status":"publish","type":"publication","link":"https:\/\/cri1149.fr\/en\/publication\/treatment-of-hepatitis-c-virus-infection-with-direct-acting-antiviral-agents-100-cure\/","title":{"rendered":"Treatment of hepatitis C virus infection with direct-acting antiviral agents: 100% cure?"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"category_publication":[],"class_list":["post-15816","publication","type-publication","status-publish","hentry"],"acf":{"numero_de_publication":"Liver Int .","date_de_publication":"20180201","numero_doi":"","equipe":[130],"auteurs-liste":[{"texte_libre":false,"auteur-lien":13023,"auteur-text":[]},{"texte_libre":false,"auteur-lien":13117,"auteur-text":[]},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Raymond F Schinazi "}],"auteurs-manuel":"[:fr]Tarik Asselah 1, Patrick Marcellin 1, Raymond F Schinazi 2[:en]1,  1, [:]","liens_externes":null,"liens":[{"lien":"https:\/\/pubmed.ncbi.nlm.nih.gov\/29427484\/"}],"paragraphe":"[:fr]<h2 class=\"title\" style=\"text-align: justify;\">Abstract<\/h2>\r\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\r\n<p style=\"text-align: justify;\">Around 71 million people are chronically infected with HCV worldwide. HCV antiviral drug development has been remarkable. The availability of pangenotypic direct-acting antivirals with excellent efficacy and good tolerability profiles offer a unique opportunity to achieve HCV elimination worldwide. IFN-free DAA combinations can now cure HCV in more than 95% of patients with HCV infection after 8-12 weeks of treatment. Programmes to eliminate HCV must include increased screening (risk-based and universal), linkage to care, as well as increased access to treatment worldwide. In this paper, we will review the available data on recently approved direct-acting antiviral agents, with sustained virological response that reaches almost 100%.<\/p>\r\n<\/div>[:]","paragraphe_en":"[:en]<h2 class=\"title\" style=\"text-align: justify;\">Abstract<\/h2>\r\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\r\n<p style=\"text-align: justify;\">Around 71 million people are chronically infected with HCV worldwide. HCV antiviral drug development has been remarkable. The availability of pangenotypic direct-acting antivirals with excellent efficacy and good tolerability profiles offer a unique opportunity to achieve HCV elimination worldwide. IFN-free DAA combinations can now cure HCV in more than 95% of patients with HCV infection after 8-12 weeks of treatment. Programmes to eliminate HCV must include increased screening (risk-based and universal), linkage to care, as well as increased access to treatment worldwide. In this paper, we will review the available data on recently approved direct-acting antiviral agents, with sustained virological response that reaches almost 100%.<\/p>\r\n<\/div>[:]","documents":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Treatment of hepatitis C virus infection with direct-acting antiviral agents: 100% cure? - CRI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cri1149.fr\/publication\/treatment-of-hepatitis-c-virus-infection-with-direct-acting-antiviral-agents-100-cure\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Treatment of hepatitis C virus infection with direct-acting antiviral agents: 100% cure? - CRI\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cri1149.fr\/publication\/treatment-of-hepatitis-c-virus-infection-with-direct-acting-antiviral-agents-100-cure\/\" \/>\n<meta property=\"og:site_name\" content=\"CRI\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/CRI-Centre-de-recherche-sur-linflammation-100116118884153\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-11T14:48:01+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cri1149.fr\\\/publication\\\/treatment-of-hepatitis-c-virus-infection-with-direct-acting-antiviral-agents-100-cure\\\/\",\"url\":\"https:\\\/\\\/cri1149.fr\\\/publication\\\/treatment-of-hepatitis-c-virus-infection-with-direct-acting-antiviral-agents-100-cure\\\/\",\"name\":\"Treatment of hepatitis C virus infection with direct-acting antiviral agents: 100% cure? 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