{"id":15370,"date":"2020-02-04T10:58:13","date_gmt":"2020-02-04T09:58:13","guid":{"rendered":"https:\/\/cri1149.fr\/?post_type=publications&#038;p=15370"},"modified":"2025-09-11T16:48:01","modified_gmt":"2025-09-11T14:48:01","slug":"gastric-bypass-specifically-impairs-liver-parameters-as-compared-with-sleeve-gastrectomy-independently-of-evolution-of-metabolic-disorders","status":"publish","type":"publication","link":"https:\/\/cri1149.fr\/en\/publication\/gastric-bypass-specifically-impairs-liver-parameters-as-compared-with-sleeve-gastrectomy-independently-of-evolution-of-metabolic-disorders\/","title":{"rendered":"Gastric bypass specifically impairs liver parameters as compared with sleeve gastrectomy, independently of evolution of metabolic disorders."},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false},"category_publication":[],"class_list":["post-15370","publication","type-publication","status-publish","hentry"],"acf":{"numero_de_publication":"Surg Obes Relat Dis","date_de_publication":"20190215","numero_doi":"","equipe":[131],"auteurs-liste":[{"texte_libre":false,"auteur-lien":13241,"auteur-text":""},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Sami O"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Calabrese D"},{"texte_libre":false,"auteur-lien":13105,"auteur-text":""},{"texte_libre":false,"auteur-lien":13075,"auteur-text":""},{"texte_libre":false,"auteur-lien":13240,"auteur-text":""}],"auteurs-manuel":"","liens_externes":null,"liens":[{"lien":"https:\/\/www.ncbi.nlm.nih.gov\/m\/pubmed\/30598254\/?i=4&from=le%20gall,%20m%202019"}],"paragraphe":"[:fr]<h3 class=\"no_b_m copper\" style=\"text-align: justify;\">Abstract<\/h3>\r\n<p class=\"no_t_m\" style=\"text-align: justify;\"><span class=\"sub_abstract_label\">BACKGROUND:\u00a0<\/span>Numerous studies have shown that Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) differently affect metabolic disorders associated with obesity. While bariatric surgery has been shown to improve nonalcoholic fatty liver disease, very few studies have compared liver parameters after both procedures.<\/p>\r\n<p class=\"no_t_m\" style=\"text-align: justify;\"><span class=\"sub_abstract_label\">OBJECTIVES:\u00a0<\/span>To compare the evolution of liver parameters after SG and RYGB and their relationships with improvement of metabolic disorders.<\/p>\r\n<p class=\"no_t_m\" style=\"text-align: justify;\"><span class=\"sub_abstract_label\">METHODS:\u00a0<\/span>Metabolic parameters and abdominal ultrasonography were recorded before and 1 year after bariatric surgery in all patients who underwent SG or RYGB between 2004 and 2016 in our institution.<\/p>\r\n<p class=\"no_t_m\" style=\"text-align: justify;\"><span class=\"sub_abstract_label\">SETTING:\u00a0<\/span>University hospital, Colombes, France.<\/p>\r\n<p class=\"no_t_m\" style=\"text-align: justify;\"><span class=\"sub_abstract_label\">RESULTS:\u00a0<\/span>Five hundred thirty-three patients (15% men, age 43 \u00b1 11 yr) were analyzed, including 326 who underwent RYGB and 207 who underwent SG. Before surgery, body mass index (44.7 \u00b1 5.7 versus 44.4 \u00b1 7.4 kg\/m\u00b2) and metabolic parameters were not significantly different. One year after surgery, RYGB induced greater weight loss (31.9 \u00b1 7.7 versus 28.6 \u00b1 8.3 %, P &lt; .001). Metabolic parameters improved in both groups, but fasting insulin, low-density lipoprotein cholesterol, C-reactive protein, and ferritin were lower after RYGB (P &lt; .001). In contrast, transaminases were higher after RYGB compared with SG (alanine aminotransferase: 31.6 \u00b1 18.7 versus 22.6 \u00b1 7.7 IU\/L; P &lt; .001). The persistence of alanine aminotransferase &gt;34 IU\/L (27% versus 7% of patients, P &lt; .001) was independent of the persistence of steatosis on ultrasonography (39% versus 37% of patients) 1 year after RYGB and SG, respectively.<\/p>\r\n<p class=\"no_t_m\" style=\"text-align: justify;\"><span class=\"sub_abstract_label\">CONCLUSION:\u00a0<\/span>Despite a greater improvement of metabolic disorders, RYGB has less beneficial effect on liver parameters compared with SG. Further studies are required to define the mechanisms explaining these differences between both procedures.<\/p>[:]","paragraphe_en":"","documents":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Gastric bypass specifically impairs liver parameters as compared with sleeve gastrectomy, independently of evolution of metabolic disorders. - CRI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cri1149.fr\/publication\/gastric-bypass-specifically-impairs-liver-parameters-as-compared-with-sleeve-gastrectomy-independently-of-evolution-of-metabolic-disorders\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gastric bypass specifically impairs liver parameters as compared with sleeve gastrectomy, independently of evolution of metabolic disorders. - 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