{"id":78008,"date":"2023-05-11T13:05:11","date_gmt":"2023-05-11T11:05:11","guid":{"rendered":"https:\/\/cri1149.fr\/actualites\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/"},"modified":"2023-05-11T13:05:11","modified_gmt":"2023-05-11T11:05:11","slug":"vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al","status":"publish","type":"post","link":"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/","title":{"rendered":"Vascular complications in cirrhosis: a review published in CGH by PE Rautou et al"},"content":{"rendered":"<p style=\"text-align: justify;\">Much has evolved over the past 25 years regarding the coagulopathy of liver disease. Paradoxically, this form of coagulopathy is relatively hypercoagulable despite the common clinical impression of a hemorrhagic tendency. The latter is largely driven by portal-mesenteric venous pressure (i.e. portal hypertension) and has little to do with hemostatic pathways. It cannot be emphasized enough that the INR really does not offer a meaningful measure in this situation and may lead to interventions such as FFP that can actually worsen portal pressure and hence pressure-driven bleeding. With regard to procedure-related bleeding, we point out substantial differences in the definition of high risk procedures and we have proposed a new operational definition dependent on the applicability of local hemostatic measures, although this requires further investigation. The common occurrence of venous thrombosis in these patients requires careful consideration of hemostatic pathways and overall risk and benefit of intervention. The decision regarding anti-coagulation therapy needs to be driven by a global assessment including history of non-portal hypertensive related bleeding, but also by fall risk in patients prone to encephalopathy which can result in head trauma. This is probably best estimated by frailty but has yet to be adequately investigated. In the background of these concerns, several super-imposed and complicated conditions including infections and renal dysfunction should be taken into account. Inherited forms of thrombophilia in the setting of cirrhosis perhaps do not outweigh the thrombophilia inherent to liver disease but warrant further consideration.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-66505 aligncenter\" src=\"https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-263x300.jpg\" alt=\"\" width=\"715\" height=\"816\" srcset=\"https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-263x300.jpg 263w, https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-898x1024.jpg 898w, https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-768x876.jpg 768w, https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-1346x1536.jpg 1346w, https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-947x1080.jpg 947w, https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-624x712.jpg 624w, https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-1320x1506.jpg 1320w, https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose.jpg 1619w\" sizes=\"auto, (max-width: 715px) 100vw, 715px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\">Link publication :<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37121529\/\"> https:\/\/pubmed.ncbi.nlm.nih.gov\/37121529\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Much has evolved over the past 25 years regarding the coagulopathy of liver disease. Paradoxically, this form of coagulopathy is relatively hypercoagulable despite the common clinical impression of a hemorrhagic [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"footnotes":""},"categories":[328],"tags":[],"class_list":["post-78008","post","type-post","status-publish","format-standard","hentry","category-news-of-the-month"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Vascular complications in cirrhosis: a review published in CGH by PE Rautou et al - CRI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vascular complications in cirrhosis: a review published in CGH by PE Rautou et al - CRI\" \/>\n<meta property=\"og:description\" content=\"Much has evolved over the past 25 years regarding the coagulopathy of liver disease. Paradoxically, this form of coagulopathy is relatively hypercoagulable despite the common clinical impression of a hemorrhagic [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/\" \/>\n<meta property=\"og:site_name\" content=\"CRI\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/CRI-Centre-de-recherche-sur-linflammation-100116118884153\" \/>\n<meta property=\"article:published_time\" content=\"2023-05-11T11:05:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1619\" \/>\n\t<meta property=\"og:image:height\" content=\"1847\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Julien Tourneur-Marsille\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Julien Tourneur-Marsille\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/\"},\"author\":{\"name\":\"Julien Tourneur-Marsille\",\"@id\":\"https:\/\/cri1149.fr\/#\/schema\/person\/8d52142957854ee6b1081a095b93ffb6\"},\"headline\":\"Vascular complications in cirrhosis: a review published in CGH by PE Rautou et al\",\"datePublished\":\"2023-05-11T11:05:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/\"},\"wordCount\":264,\"publisher\":{\"@id\":\"https:\/\/cri1149.fr\/#organization\"},\"image\":{\"@id\":\"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/cri1149.fr\/wp-content\/uploads\/2023\/05\/PE_complication_cirrhose-263x300.jpg\",\"articleSection\":[\"News of the month\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/\",\"url\":\"https:\/\/cri1149.fr\/en\/news-of-the-month\/vascular-complications-in-cirrhosis-a-review-published-in-cgh-by-pe-rautou-et-al\/\",\"name\":\"Vascular complications in cirrhosis: a review published in CGH by PE Rautou et al - 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