{"id":13971,"global_id":"cri1149.fr\/en\/?id=13971","global_id_lineage":["cri1149.fr\/en\/?id=13971"],"author":"9","status":"publish","date":"2019-09-23 13:09:28","date_utc":"2019-09-23 12:09:28","modified":"2019-09-23 13:12:39","modified_utc":"2019-09-23 12:12:39","url":"https:\/\/cri1149.fr\/en\/evenement\/13971\/","rest_url":"https:\/\/cri1149.fr\/en\/wp-json\/tribe\/events\/v1\/events\/13971","title":"Les mercredis Bichat-beaujon","description":"<p style=\"text-align: center;\"><strong>&#8220;Impact of neutrophil-venular wall interactions<\/strong><br \/>\n<strong>in experimental models of inflammation&#8221;<\/strong><\/p>\n<p style=\"text-align: center;\"><strong>by<\/strong><\/p>\n<p style=\"text-align: center;\"><b>Lo\u00efc Rolas<\/b><\/p>\n<p style=\"text-align: justify;\">\u00ab Ageing is the primary risk factor for inflammatory disorders and whilst ageing-associated changes in immune cell functions have been extensively studied, very little is known regarding age-associated changes in neutrophil-vessel wall interactions during inflammation. Using cutting-edge imaging platforms (CMR advance bio-imaging affinity) and novel neutrophil-specific mouse models, my aim is to address this issue, hypothesising that ageing, in particular vascular ageing, supports disrupted neutrophil trafficking.<\/p>\n<p style=\"text-align: justify;\">Collectively, I identify novel neutrophil behaviours and exaggerated generation of pro-inflammatory mediators in inflamed aged vasculatures. The work generated offers potential mechanisms that could be targeted for suppressing ageing-associated aberrant neutrophil trafficking and tissue damage\u201d<\/p>\n<p>Avec le soutien d\u2019Inflamex<\/p>\n<p><a href=\"http:\/\/www.cri1149.fr\/wp-content\/uploads\/2014\/12\/Logo-inflamex-615x250-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-4007 \" src=\"http:\/\/www.cri1149.fr\/wp-content\/uploads\/2014\/12\/Logo-inflamex-615x250-1.jpg\" alt=\"Logo-inflamex-615x250-1\" width=\"193\" height=\"77\" \/><\/a><\/p>","excerpt":"","slug":"13971","image":false,"all_day":true,"start_date":"2019-10-02 00:00:00","start_date_details":{"year":"2019","month":"10","day":"02","hour":"00","minutes":"00","seconds":"00"},"end_date":"2019-10-02 23:59:59","end_date_details":{"year":"2019","month":"10","day":"02","hour":"23","minutes":"59","seconds":"59"},"utc_start_date":"2019-10-01 22:00:00","utc_start_date_details":{"year":"2019","month":"10","day":"01","hour":"22","minutes":"00","seconds":"00"},"utc_end_date":"2019-10-02 21:59:59","utc_end_date_details":{"year":"2019","month":"10","day":"02","hour":"21","minutes":"59","seconds":"59"},"timezone":"UTC+1","timezone_abbr":"UTC+1","cost":"","cost_details":{"currency_symbol":"","currency_code":"","currency_position":"prefix","values":[]},"website":"","show_map":false,"show_map_link":false,"hide_from_listings":false,"sticky":false,"featured":false,"categories":[{"name":"Les Mercredis du CRI (MCRI)","slug":"mcri","term_group":0,"term_taxonomy_id":119,"taxonomy":"tribe_events_cat","description":"Affiche les \u00e9v\u00e8nements scientifiques organis\u00e9s par le CRI dans ses locaux.\r\nLes Mercredi du CRI (MCRI), ce sont des chercheurs du CRI ou des invit\u00e9s ext\u00e9rieurs qui se relaient tous les mercredis pour pr\u00e9senter leur recherche et les avanc\u00e9es. Ce d\u00e9roule en hybride (pr\u00e9sentiel + Zoom).","parent":0,"count":250,"filter":"raw","id":119,"urls":{"self":"https:\/\/cri1149.fr\/en\/wp-json\/tribe\/events\/v1\/categories\/119","collection":"https:\/\/cri1149.fr\/en\/wp-json\/tribe\/events\/v1\/categories"}}],"tags":[],"venue":[],"organizer":[],"custom_fields":[],"json_ld":{"@context":"http:\/\/schema.org","@type":"Event","name":"Les mercredis Bichat-beaujon","description":"&lt;p&gt;&quot;Impact of neutrophil-venular wall interactions in experimental models of inflammation&quot; by Lo\u00efc Rolas \u00ab Ageing is the primary risk factor for inflammatory disorders and whilst ageing-associated changes in immune cell [&hellip;]&lt;\/p&gt;\\n","url":"https:\/\/cri1149.fr\/en\/evenement\/13971\/","eventAttendanceMode":"https:\/\/schema.org\/OfflineEventAttendanceMode","eventStatus":"https:\/\/schema.org\/EventScheduled","startDate":"2019-10-02T00:00:00+02:00","endDate":"2019-10-02T23:59:59+02:00","performer":"Organization"}}