Presentation

The HGE department brings is composed of 7 teams covering the entire field of Hepatology, Gastroenterology and Pancreatology.

 

Our general objectives are to study the impact of environmental factors (nutrition, alcohol, tobacco, viruses, drugs …) on the progression of chronic diseases of the liver (INVolVED, INDiD, HEPA-VASC Atip-Avenir:, VHEP) , gastrointestinal tract and pancreas (PIMS, GMI, INDiD) using molecular, cellular and imaging approaches (LBI) and combining animal models as well as cohorts of patients.

We aim at better understanding the mechanisms involved in the deregulation of inflammatory mechanisms, as well as to validate new imaging biomarkers.

The close interaction between HGE Department team members and clinicians of the Paris Nord Val de Seine Hospitals University (HUPNVS) responsible for reference centers for rare digestive diseases and/or members of labeled networks, allows the development of strong translational research.

Teams of the Department are founding members of the:

  • Federation of Hospital University (FHU) MOSAIC «Multiscale Optimized Strategy for Artificial Intelligence-based Imaging Biomarkers Digestive Cancer»
  • Laboratory of Excellence (Labex) Inflamex,
  • University Hospital Research in Health (RHU) Quid-NASH  «Virtual liver Biopsy»

In addition all the teams participate in various European and international programs.

 

Team INVolVED is a founding member of an International Associated Laboratory (LIA) and since March 2018, the HGE’s department has been twinned with the Institute of Liver & Biliary Sciences, New Delhi, India.

The HGE department is involved in a Master 2 program at the University of Paris, on physiology/pathophysiology of the liver, gastrointestinal and the pancreas and the teams propose practical internships for the students.

 

Reference Centers and Labelled Networks link to the HGE’s department:

Reference Center for Vascular Liver Diseases  

(http://recherche-hupnvs.aphp.fr/centre-de-reference-maladies-vasculaires-foie-crmvf/)

Reference Center for Rare Digestive Diseases (MARDI) 

(https://www.fimatho.fr/mardi)

Reference Center for Rare Pancreas Diseases (PaRaDis)

 (https://www.maladie-pancreas.fr/)

Paris North Integrated Reference Center for Obesity

(http://www.cinfo.fr/)

Leader

Teams