Cet événement a réuni plus de 100 participants, parmi lesquels des chercheurs, cliniciens, jeunes investigateurs et étudiants, autour d’une thématique centrale : Des interactions cellulaires à la communication inter-organes

Tout au long de la journée, les intervenants et participants ont exploré plusieurs enjeux scientifiques majeurs, notamment :

• L’inflammation rénale et la fibrose dans les maladies chroniques
• Les interactions poumon-articulation à travers l’exemple de la polyarthrite rhumatoïde
• Les organoïdes immunitaires autologues pour étudier le développement des cancers pédiatriques
• Le système du complément comme acteur clé de la communication intercellulaire

Le programme a également mis en lumière plusieurs short talks de grande qualité, illustrant le dynamisme, le talent et l’engagement de la nouvelle génération de chercheurs.

Prix des meilleures présentations orales

Toutes nos félicitations à Sophie de Tocqueville et Louis Berthet, lauréats des Best Oral Presentation Awards.

Nous remercions chaleureusement l’ensemble des intervenants, modérateurs, participants et organisateurs qui ont contribué au succès de cette première édition.

Un grand merci également à la Faculté de Cochin pour son accueil et la mise à disposition de ses locaux.

Rendez-vous pour la suite

Cette première édition marque le début d’une belle dynamique scientifique. Restez connectés pour découvrir prochainement les informations concernant la 2e édition de l’INFIBREX & INFIRE Scientific Day.

L’article Retour sur la première INFIBREX & INFIRE Scientific Day – 10 avril 2026 est apparu en premier sur CRI.

Le point marquant est que la maladie ne touche pas seulement les poumons. Les patients présentent souvent aussi des signes visibles sur la peau, les ongles, les cheveux, la bouche ou les dents, ce qui peut aider à suspecter le diagnostic plus tôt. Dans l’étude, plusieurs patients avaient également des anomalies du sang, suggérant que l’atteinte peut être plus large qu’une simple maladie pulmonaire.

En pratique, l’article souligne l’importance de penser à une cause génétique chez les patients adultes ayant une fibrose pulmonaire, surtout lorsqu’elle s’accompagne de signes “extra-pulmonaires” comme un vieillissement prématuré des cheveux, des ongles fragiles ou des anomalies de la pigmentation.

Le message principal est donc le suivant : les mutations de DKC1 peuvent provoquer une fibrose pulmonaire sévère chez l’adulte, avec un pronostic sérieux, et certains signes cliniques peuvent aider à la reconnaître plus tôt.

https://cri1149.fr/publication/les-patients-adultes-de-sexe-masculin-porteurs-de-mutations-du-gene-dkc1-presentent-une-fibrose-pulmonaire-dapparition-precoce-et-un-pronostic-severe

L’article Une mutation du gène DKC1 associée à une fibrose pulmonaire sévère chez l’adulte est apparu en premier sur CRI.

On March 16, 2026, Inserm’s Annual Day was held at the Maison de la Chimie in Paris. The event brought together scientific and administrative managers from the Institute’s various structures.

Themes at the heart of scientific news

The day was punctuated by a number of speeches and round tables on current topics, such as Inserm’s strategy, imaging and artificial intelligence, misinformation in healthcare, as well as the evolution of evaluation practices and the challenges of clinical research.

Presence of the Inflammation Research Center (U1149)

Researchers from the Inflammation Research Center (U1149) took part in the event, alongside other Inserm research units and departments.

A meeting between research players

In addition to the presentations, the day was also an opportunity for exchanges between the Institute’s various players, enabling them to share information and feedback on current developments in healthcare research.

Pierre Launay, Emilie Viennois, Philippe Garteiser, Emmanuel Weiss, Arnaud Mailleux

L’article Inserm Day 2026: a time for exchanging views on research issues est apparu en premier sur CRI.

The iMAP platform – Multimodal Imaging Applied to Pathology is proud to announce that it has been awarded the IBiSA label for a period of two years.

In early 2025, iMAP applied to join the IBiSA network, which supports technological platforms in their technological and methodological development projects, as well as in their quality management processes.

Following the evaluation of the scientific dossier and an on-site visit, iMAP was granted the IBiSA label, recognizing its expertise, strong commitment, and openness to the scientific community.

Bringing together researchers and pathologists within a unique environment, iMAP offers comprehensive expertise in multimodal imaging, including histology, immunohistochemistry, multiplex immunofluorescence, and mass spectrometry imaging.

The platform also provides transcriptomic and bioinformatics analyses, enabling the integration of molecular data with morphological features to better understand tissue heterogeneity, particularly in the fields of inflammation and cancer.

A well-deserved recognition for the iMAP team, the CRI – Centre de Recherche sur l’Inflammation, and all their partners Bruker @CelldiveLeica Microsystems @IBiSA @iMAP @MultimodalImaging Université Paris Cité CNRS Inserm hopital beaujon Valerie Paradis Helene Cazier Diana MENDES Jerome Cros Rémy Nicolle

L’article iMAP platform awarded IBiSA label est apparu en premier sur CRI.

This redesign is part of our drive to modernize our communications and improve access to information about our research activities, teams and projects.

This new tool is designed to enhance the visibility of our work and facilitate exchanges with all our partners and the scientific community.

L’article CRI unveils its new website est apparu en premier sur CRI.

FIBROCUT – Targeting immune checkpoints in idiopathic pulmonary fibrosis

Scientific coordinator: Georges Helou – Inflammation and fibrosis in lung diseases team – UMR 1149 – CRI Inflammation Research Center

Equipment : VF-510-0Z Compresstome® Vibrating Microtome

Idiopathic pulmonary fibrosis (IPF) is a chronic, fatal lung disease. Recent studies have confirmed the key role of immune cells in regulating the progression of IPF. Immune checkpoints, receptors that modulate the intensity of the immune response, have become innovative targets in cancer. Given the common molecular pathways between IPF and cancer, and the central role of the immune system in IPF, we investigated the involvement of immune checkpoints in this disease. Using transcriptomic analysis and flow cytometry, we identified two immune checkpoints relevant to IPF and demonstrated their modulatory roles. We now aim to implement ex vivo translational models using precision lung sections (PCLS) from murine and human lung biopsies to assess the therapeutic potential of targeting these receptors in pulmonary fibrosis. The generation of viable and structurally preserved 3D PCLS cultures requires a high-precision vibratome system, hence the interest of this funding request.

L’article George Helou secures funding for FIBROCUT. est apparu en premier sur CRI.

L’article Reproducibility and Lego workshop est apparu en premier sur CRI.

To mark the Fête de la Science (Thursday, October 9),AP-HP, Assistance Publique – Hôpitaux de Paris, has initiated and supported an original scientific mediation project: an educational escape game designed and run by doctors and researchers at our Research Center.

👩‍🔬 Students had 1 hour to understand why the liver was becoming diseased and threatening to contaminate other cells, and to find the right treatment before it was too late!

This initiative welcomed four classes from Ville de Clichy-la-Garenne to the Beaujon hospital, in a fun and educational atmosphere, to bring science to life and make it accessible to all.

Workshop prepared by Valerie Paradis and researchers/engineers Aurélie Beaufrère, Matthieu Tihy, Camille Pignolet, Gabriel Cordova, Miguel Albuquerque, Lucy Bourlet,Meriem Marref, Arnaud Sénécaut, Olivier Fourati, Ghalia Ben Ghedifa, Samira Laouirem, Killian Véron, Lucie Gomes, Norma Bloy, and the Anatomical Pathology Department.

L’article The Festival of Science est apparu en premier sur CRI.

Well done to our young researchers from the Association des Jeunes Chercheurs de l’Hopital Grand Paris Nord for organizing and holding this beautiful and rich scientific day!

Thanks to the speakers for the quality of their presentations, and to all participants for their curiosity and enthusiasm!

The day highlighted the richness and diversity of the work being carried out by the young researchers in our teams.
Between presentations, discussions and the sharing of experiences, the day was a reminder of the extent to which research is above all a collective adventure.

Once again, this year’s event confirmed that the next generation of scientists is promising, passionate and full of ideas.

L’article Back to JCBB 2025 est apparu en premier sur CRI.

L’article CRI takes part in Odyssea est apparu en premier sur CRI.