Presentation
The HGE department is composed of 7 teams covering the entire field of Hepatology, Gastroenterology and Pancreatology.
Our general objectives are to study the impact of environmental factors (nutrition, alcohol, tobacco, viruses, drugs …) and inflammation on the progression of chronic diseases of the liver and on disorders of the gastrointestinal tract and the pancreas using molecular, cellular and imaging approaches and combining animal models as well as cohorts of patients.
We aim at better understanding the mechanisms involved in the deregulation of inflammatory mechanisms, as well as to validate new biomarkers for this spectrum of diseases.
The close interaction between HGE Department team members and clinicians of the Paris Nord Val de Seine Hospitals University (HUPNVS) responsible for reference centers for rare digestive diseases and/or members of labeled networks, allows the development of strong translational research.
Teams of the Department are founding members of various excellence programs such as FHU (Fédération Hospitalo-Universitaire) MOSAIC and PaCeMM, Labex (Laboratoire d’Excellence) Inflamex RHU (Recherche Hospitalo-Universitaire) Quid-NASH.
The HGE department is twinned with the Institute of Liver & Biliary Sciences, New Delhi India, with which it has an International Associated Laboratory.
The HGE department is involved in a Master 2 program at the University of Paris, on physiology/pathophysiology of the liver, gastrointestinal and the pancreas and the teams propose practical internships for the students.
Reference Centers and Labelled Networks link to the HGE’s department:
Reference Center for Vascular Liver Diseases
(http://recherche-hupnvs.aphp.fr/centre-de-reference-maladies-vasculaires-foie-crmvf/)
Reference Center for Rare Digestive Diseases (MARDI)
(https://www.fimatho.fr/mardi)
Reference Center for Rare Pancreas Diseases (PaRaDis)
(https://www.maladie-pancreas.fr/)
Paris North Integrated Reference Center for Obesity
